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Postdoctoral Research Fellowship in Immunopathophysiology

Employer
Global Academy Jobs
Location
France
Closing date
Oct 15, 2019

Job Details

Job description

A 3-year postdoctoral position (1+2) to study lupus nephritis pathophysiology is available in the Basophil, Mast cell and Immunopathology (BMI) team of the Centre for Research on Inflammation (CRI, INSERM U1149 CNRS ERL8252 University of Paris, Laboratoire d'Excellence INFLAMEX) in close collaboration with the Nephrology and Internal Medicine departments of the Bichat Hospital, University of Paris, in Paris, France. The expected starting date is November 1st 2019.

More about the position

Systemic Lupus Erythematosus (SLE) is an autoimmune disease evolving in flares triggered by innate immune stimuli that aggravate associated renal pathology that can be amplified by basophils. The project will aim at defining in in vitro models, animal models and human samples how the crosstalk between mast cells and basophils may trigger lupus flares and associated renal disease. The team involved in this project has a long and productive history in deciphering the role of immune cells and associated molecular mechanisms in renal and non-renal autoimmune disorders (Charles et al., Immunity 2009, Nat Med 2010 and 2012; Dema et al., J Exp Med 2014; Clement et al., J Autoimmun 2015; Danelli et al., J Immunol 2017; Pellefigues et al., Nat Commun 2018).

The successful candidate will work under the direct supervision of Dr Nicolas Charles (BMI, CRI). Translational aspects using human samples will be done in close collaboration with the Nephrology and Internal Medicine departments of the Bichat Hospital (Prof. Eric Daugas and Profs. Karim Sacré and Thomas Papo, members of BMI).

Company

Global Academy Jobs works with over 250 universities worldwide to promote academic mobility and international research collaboration. Global problems need international solutions. Our jobs board and emails reach the academics and researchers who can help.

"The globalisation of higher education continues apace, driving in turn the ongoing development of the global knowledge economy, striving for solutions to the world’s problems and educating a next generation of leaders and contributors."

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