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Postdoc - develop innovative neuroblastoma models

Employer
Global Academy Jobs
Location
France
Closing date
Sep 29, 2019

Job Details

Starting on October 2019.

Available for highly motivated post-doctoral fellow interested in conducting interdisciplinary research using in-vitro and in-silico approaches to develop innovative neuroblastoma models and use them to better understand the mechanisms of resistance to treatment in these pathologies. Successful candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities.

The candidate should achieve the development of robust strategies & protocols to generate and characterize neuroblastoma organoid models from tumoral samples and from healthy tissues upon genetic engineering.

Moreover, the candidate will use these organoid tools to address the intratumoral heterogeneity role in cell death resistance notably upon treatments. Finally, the candidate will be involved in writing reports, publications and grant applications.

About the lab

The establishment of cancer-derived organoids has recently begun to emerge as a prominent and promising tool to enhance our understanding of human cancers (Broutier et al., nature protocols 2016 & Broutier et al., nature medicine 2017). However, such models have as yet not been developed for pediatric cancers. The research program that we develop in the C3 lab forms part of this perspective with the objective to elaborate innovative organoid models to address pediatric cancers specificities and complexity, with a special focus on the mechanisms of resistance to treatments. We are affiliated to the Cancer Research Centre of Lyon (CRCL -INSERM U1052 / CNRS 5286) and to the Centre Léon Bérard's Pediatric hospital (IHOPE). The CRCL is amongst the most prestigious cancer research center in France and the IHOPE is a major reference pediatric cancer center. Our group is therefore composed of both researchers, clinicians and pathologists.

Company

Global Academy Jobs works with over 250 universities worldwide to promote academic mobility and international research collaboration. Global problems need international solutions. Our jobs board and emails reach the academics and researchers who can help.

"The globalisation of higher education continues apace, driving in turn the ongoing development of the global knowledge economy, striving for solutions to the world’s problems and educating a next generation of leaders and contributors."

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