Postdoc - develop innovative neuroblastoma models
- Employer
- Global Academy Jobs
- Location
- France
- Closing date
- Sep 29, 2019
View more
- Sector
- Science, Life Sciences, Cell and Molecular Biology, Pharmaceutical, Business Development
- Hours
- Full Time
- Organization Type
- University and College
- Jobseeker Type
- Academic (e.g. 'Lecturer')
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Job Details
Starting on October 2019.
Available for highly motivated post-doctoral fellow interested in conducting interdisciplinary research using in-vitro and in-silico approaches to develop innovative neuroblastoma models and use them to better understand the mechanisms of resistance to treatment in these pathologies. Successful candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities.
The candidate should achieve the development of robust strategies & protocols to generate and characterize neuroblastoma organoid models from tumoral samples and from healthy tissues upon genetic engineering.
Moreover, the candidate will use these organoid tools to address the intratumoral heterogeneity role in cell death resistance notably upon treatments. Finally, the candidate will be involved in writing reports, publications and grant applications.
About the lab
The establishment of cancer-derived organoids has recently begun to emerge as a prominent and promising tool to enhance our understanding of human cancers (Broutier et al., nature protocols 2016 & Broutier et al., nature medicine 2017). However, such models have as yet not been developed for pediatric cancers. The research program that we develop in the C3 lab forms part of this perspective with the objective to elaborate innovative organoid models to address pediatric cancers specificities and complexity, with a special focus on the mechanisms of resistance to treatments. We are affiliated to the Cancer Research Centre of Lyon (CRCL -INSERM U1052 / CNRS 5286) and to the Centre Léon Bérard's Pediatric hospital (IHOPE). The CRCL is amongst the most prestigious cancer research center in France and the IHOPE is a major reference pediatric cancer center. Our group is therefore composed of both researchers, clinicians and pathologists.
Available for highly motivated post-doctoral fellow interested in conducting interdisciplinary research using in-vitro and in-silico approaches to develop innovative neuroblastoma models and use them to better understand the mechanisms of resistance to treatment in these pathologies. Successful candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities.
The candidate should achieve the development of robust strategies & protocols to generate and characterize neuroblastoma organoid models from tumoral samples and from healthy tissues upon genetic engineering.
Moreover, the candidate will use these organoid tools to address the intratumoral heterogeneity role in cell death resistance notably upon treatments. Finally, the candidate will be involved in writing reports, publications and grant applications.
About the lab
The establishment of cancer-derived organoids has recently begun to emerge as a prominent and promising tool to enhance our understanding of human cancers (Broutier et al., nature protocols 2016 & Broutier et al., nature medicine 2017). However, such models have as yet not been developed for pediatric cancers. The research program that we develop in the C3 lab forms part of this perspective with the objective to elaborate innovative organoid models to address pediatric cancers specificities and complexity, with a special focus on the mechanisms of resistance to treatments. We are affiliated to the Cancer Research Centre of Lyon (CRCL -INSERM U1052 / CNRS 5286) and to the Centre Léon Bérard's Pediatric hospital (IHOPE). The CRCL is amongst the most prestigious cancer research center in France and the IHOPE is a major reference pediatric cancer center. Our group is therefore composed of both researchers, clinicians and pathologists.
Company
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