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Research Technician - Institute of Cancer and Genomic Sciences

Employer
Global Academy Jobs
Location
United Kingdom
Salary
£22,407.00 - £24,411.00
Closing date
Oct 4, 2019

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Job Details

Position Details

Institute of Cancer and Genomic Sciences

University of Birmingham, Edgbaston, Birmingham UK

Band 500

Full time starting salary is normally in the range £22,722 to £24,411. With potential progression once in post to £28,259 a year.

Fixed term contract for 3 years

Closing Date: 4 October 2019

Job Purpose

A technician position in Dr Aga Gambus lab funded by BBSRC project grant. This position is to support research aiming at understanding regulation of TRAIP ubiquitin ligase during cell cycle.

Main duties
RESEARCH - 75%
Job specific duties:
- Expression of recombinant proteins in bacteria and insect cells systems (tissue culture techniques)
- Affinity purification of recombinant proteins
- Cloning and mutagenesis of plasmids designed to express recombinant proteins
- Affinity purification of antibodies
- In vitro ubiquitylation and phosphorylation reactions
- Assistance with preparation of Xenopus laevis egg extract
- Standard protein techniques: gel electrophoresis, western blotting...
- Helping students and other members of the lab with their protein expression/purifications
- Biochemical analysis of DNA replication reactions in Xenopus laevis egg extract

HEALTH AND SAFETY/ENVIRONMENTAL ISSUES - 10%

• Enabling staff and students, working within the area of responsibility, to comply with all basic University / College Health & Safety policies This will include compliance by all staff with current rules governing work with COSHH, genetically modified organisms (GMOs), biological samples, human tissue, radioactive materials and schedule 5 toxins etc. Ensure all required assessments are in place approved and up to date.
• Maintaining records both paper and computer based as appropriate.
• Carrying out regular maintenance processes such as flushing eye wash stations as appropriate and ensuring records are maintained.
• Reporting any breaches or non-compliance with H&S procedures to the PI, Technical Manager, Laboratory Manager or College Safety Adviser.
• Upholding the correct waste disposal stream as governed by College and local policy for laboratory, recycled and general waste
• Adopt a proactive attitude to assisting with and implementing carbon reduction and energy saving measures

GENERAL ADMINISTRATION AND ORGANISATION - 8%
The post holder will assist with the daily administration and organisation of the work area. These duties include:
• Maintaining stocks of consumables, if necessary, creating purchase order requisitions for the College finance office or via web based ordering system
• Receipt and correct storage of consumables and chemical reagents.
• Ensuring that the facilities are maintained in a clean, functional and safe condition, reporting any problems through the appropriate channels.
• Ensuring the best use of equipment through booking systems, if appropriate
• Reporting any problems with equipment or services to the line manager as appropriate.
• Any other duties commensurate with the grade and skill base of the post holder as directed by either the Principle investigator for research based activities or the Technical Managers for non research based activities

OTHER DUTIES - 7%
• In collaboration with the Laboratory Manager or supervisor the post holder will take an active role in the training and mentoring process for junior or newly appointed staff/students
• To actively engage in the Personal Development Process
• To contribute at a level appropriate with the grade, to internal and external audit procedures, and to regulatory inspections.
• Assist Technical Managers and/or Laboratory Managers in identifying and tracking items held on the University asset register.

Person Specification
• Degree or equivalent professional qualification in an appropriate subject
• GCSE (A*- C) or equivalent in mathematics
• In-depth practical knowledge of technical and scientific methods stated above and Good Laboratory Practice gained through extensive experience and formal qualification
• Extensive experience of similar laboratory based work
• Positive service attitude and shows courtesy in dealing with others
• Ability to organise and manage own work load and demonstrate flexibility in terms of work practices/requirements
• Ability to work under minimal supervision but function as part of a team
• Knowledge of current relevant H&S policies
• Proficiency in commonly used software packages
• Willingness to work towards professional registration

The University is committed to safeguarding and we promote safe recruitment practice, therefore all associated pre-employment checks will be undertaken before any appointment is confirmed.

Due to the nature of the work undertaken in this role all successful applicants will be subject to a satisfactory Occupational Health and/or DBS clearance prior to appointment.

We value diversity at The University of Birmingham and welcome applications from all sections of the community'

For further information please contact:

Mr David Lloyd, D.R.lloyd@bham.ac.uk , 0121 414 4000

Company

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