Senior Synthetic Chemist - South San Francisco

Apex Life Sciences
South San Francisco, California
Oct 31, 2019
Nov 16, 2019
Organization Type
Senior Chemist

Position Summary

Stratacuity is a stealth-mode therapeutics development company pioneering a novel synthetic gene editing technology to treat and cure patients with devastating rare diseases. We seek a motivated and collaborative chemist to join our team. Candidates should have a Bachelor's degree in organic chemistry with minimum of 4 years of industry experience (or minimum 2 years of experience in case of master's degree in organic chemistry) in the field of organic or peptide synthesis. The successful candidate will be part of a dynamic and rewarding work environment where the abilities to effectively communicate and function in a team environment will be essential for success.

  • Successfully prepare, purify and characterize peptide nucleic acid oligomers for Stratacuity's research efforts toward therapeutics development for rare diseases using gene editing technology
  • Maintain PNA monomer and oligomer inventory and Preparing PNA aliquots for delivery to different groups for research purpose
  • Labelling of PNA probes via solution and solid phase methodologies
  • Use and maintain the team's peptide synthesizers, HPLCs, Q-TOF and other instruments for synthesis workflow
  • Development, submission, and maintenance QC data on files as well as on internal database
  • Planning, execution, and documentation of work under the guidance of the lead chemist
  • Independent work on projects and presentation in team meetings
  • Essential Qualifications
  • Bachelor's degree with 4 years of industrial experience respectively in the field of organic or peptide synthesis
  • Hands on experience in the HPLC analysis and purification
  • Excellent communication and record keeping skills
  • Ability to multitask, able to work in a team and readily adapts to changing priorities
  • Preferred Qualifications
  • Master's degree in Chemistry with minimum 2 years of industrial experience respectively in the field of organic or peptide synthesis
  • experience using automated peptide synthesis instrumentation
  • Experience with LC-MS, especially LC coupled with Q-TOF
  • Hands on experience on preparative scale purification of peptides or oligos