Senior Scientist, Computational Structural Biologist

Just - Evotec Biologics
Seattle, Washington
Oct 31, 2019
Nov 16, 2019
Organization Type
Just is seeking a highly motivated and creative computational structural biologist to help invent and apply antibody and protein therapeutic design technologies for application in the areas of antibody humanization, therapeutic modality design, antibody developability optimization, antibody discovery library designs, and therapeutic discovery analyses. The successful candidate will interface with expertise across therapeutic development including discovery, characterization, process development, and manufacturing. The candidate will also have the ability to actively implement designs on the bench, including designed variants and display libraries .

The successful candidate must also possess strong communication and collaboration skills, a desire to learn new scientific concepts and domains, and an ability to work directly with scientific staff across multiple disciplines.

Examples of Potential Responsibilities:
  • Work independently and in teams to develop, implement, and utilize biologics therapeutic design methods
  • Work with external and internal clients on antibody therapeutic design and optimization projects
  • Collaborate with and provide computational structural biology support for the Data Science team
  • Aid in the design of antibody display libraries for discovery efforts
  • Provide structural and bioinformatic support for discovery screen results
  • Collaborate with scientific staff across multiple disciplines to accomplish goals

  • Ph.D. with 2-5 years experience with strong experience in computational structural biology
  • Strong experience in therapeutic antibody and immunogen designs
  • Strong experience with computational structural biology platforms
  • Strong drive toward innovation
  • Excellent verbal and written communication skills
  • Strong focus on quality and attention to detail
  • Possess effective task/time management organizational skills

Preferred Qualifications:
  • Experience in a commercial biotherapeutic development environment
  • Experience with the Molecular Operating Environment
  • Laboratory experience in molecular biology and antibody expression
  • Laboratory experience with epitope binning and mapping methods
  • Laboratory experience in elucidating protein-protein interactions
  • Laboratory experience with high-throughput screening and protein biochemistry methods
  • Familiarity with Next Generation Sequencing technologies
  • Familiarity with yeast display technologies
  • Ability to work in small groups as well as independently
  • Ability to organize, analyze/interpret, and effectively communicate results

About Just.Bio

Established in 2014, Just Biotherapeutics, Inc. was acquired by Evotec SE in 2019. Just.Bio, an Evotec company, is a unique platform company that integrates the design, engineering, development, and manufacture of biologics. With deep experience in the fields of protein, process and manufacturing sciences, the Just team came together to solve the scientific and technical hurdles that block access to life-changing protein therapeutics; from the design of therapeutic molecules to the design of the manufacturing plants used to produce them. Our focus is to create access and value for a global market through scientific and technological innovation. Learn more at .

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