Scientist, Cell Engineering
- Employer
- Sana Biotechnology
- Location
- South San Francisco, California, United States
- Salary
- Competitive
- Closing date
- Dec 6, 2020
View more
- Sector
- Science, Life Sciences, Cell and Molecular Biology, Genetics
- Organization Type
- Corporate
You need to sign in or create an account to save a job.
Job Details
JOB PURPOSE
Sana Biotechnology is developing advanced delivery and genome engineering technologies to enable the next generation of gene and cell therapies. We are looking for a highly motivated and creative Scientist to join our new Cell Engineering group. The successful candidate will work with colleagues to establish novel genome editing capabilities and methods that will be used to develop engineered cells for our therapeutic programs. The environment is exciting and fast-paced and offers the opportunity to work and publish at the cutting edge of gene editing research.
DUTIES & RESPONSIBILITIES
QUALIFICATIONS
Required Qualifications
Preferred Qualifications
Sana Biotechnology is developing advanced delivery and genome engineering technologies to enable the next generation of gene and cell therapies. We are looking for a highly motivated and creative Scientist to join our new Cell Engineering group. The successful candidate will work with colleagues to establish novel genome editing capabilities and methods that will be used to develop engineered cells for our therapeutic programs. The environment is exciting and fast-paced and offers the opportunity to work and publish at the cutting edge of gene editing research.
DUTIES & RESPONSIBILITIES
- Work with the group to establish and apply novel cell engineering capabilities
- Generate knock-out and knock-in critical cell lines using gene editing tools
- Isolate clonal cell lines from and verify editing via sequencing methods (Sanger/NGS) and functional assays such as flow cytometry, western blotting, qRT-PCR, microscopy
- Assist in production and purification of viral vectors
- Coordinate with cross-functional teams to expand the range and sophistication of engineerable behaviors that can be applied to our cell therapy programs
- Communicate and document findings via verbal and written methods
QUALIFICATIONS
Required Qualifications
- PhD +2 years of academic/industry experience or BA/MS +7 years academic/industry experience
- Proficiency in the culture and editing of diverse mammalian cell lines
- Strong scientific background and publication record with proven high levels of performance
- Excellent communication skills; ability to present effectively to teams with diverse backgrounds
- Ability to adapt to increasing scope and complexity of work as projects mature
- Comfortable in a fast-paced research environment with minimal direction, and able to adjust workload based upon changing priorities
Preferred Qualifications
- Experience in the production of viral vectors including lentivirus and AAV
- Familiarity with viral vector titering methods including ELISA for viral proteins like p24 and flow cytometry to measure transduction of target cells with GFP
- Demonstrated high throughput and multiplexing capabilities
- Expertise in multicolor flow cytometry and FACS sorting
- Experience with assays for measuring cellular DNA damage response
- Molecular biology skills
Company
We believe we are entering a new era of medicine. The ability to modify genes and use cells as medicines provides new tools to meaningfully change the outcome of many human diseases.
Early pioneers have made good progress, but most of what we can deliver for patients remains in front of us.
Sana was founded with the long view – bringing together great people and the best technologies to deliver on the challenging promise of engineered cells as medicines.
Three aspirations drive Sana as we look to treat patients with poor outcomes or currently untreatable diseases.
Company info
- Website
- https://sana.com/
You need to sign in or create an account to save a job.
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert