Single-cell Genomics Research Associate

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated Research Associate to join the Single-Cell Genomics Platform.
IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.
Single-cell genomics is revolutionizing our understanding of biology, from redefining our understanding of diverse cell types, to translating this knowledge to better understand disease states and their implications for therapeutics. The Research Associate will be part of the technology platform for single-cell genomics supporting the research groups of IOB.

Your position

• Isolate/prepare single cells from various tissues and cultures and perform related NGS library preparation (10X Genomics System);
• Test and set up Spatial Transcriptomics methods;
• Operate various instruments, such as FACS (FACSAria Fusion), liquid handling robot (Tecan Fluent) and nanodispenser (I-DOT).
• Implement new plate-based as well as emulsion-based protocols for specialized NGS applications in collaboration with research groups or other members of the Facility;
• Ensure the quality of existing NGS protocols;
• Prepare sequencing libraries for users of the Facility and perform the sequencing on Illumina instruments.

Your profile

• PhD degree in molecular biology, biomedical science, biotechnology or a related field;
• Minimum of 5 years research experience in Genomics. Previous experience in the single-cell field will be highly valued;
• Knowledge of liquid handling robotic platforms is an advantage but training will be provided;
• Knowledge of Unix, R and/or Python will be highly valued;
• Enthusiasm for establishing, troubleshooting and optimizing new protocols and techniques;
• Independence in the planning, execution, analysis of standard molecular biology experiments;
• Highly organized and detail-oriented;
• Good written and verbal communications skills;
• Fluency in English is a requirement, fluency in German is an advantage.

We offer you

• Highly competitive conditions in a dynamic and international research community in Basel;
• IOB is an equal-opportunity employer with family-friendly work policies.