Research Fellow in Structural Biology/Biophysics,

United Kingdom
£33,797 to £40,322 p.a.
Dec 18, 2020
Jan 17, 2021
Organization Type
University and College
Full Time
Are you an ambitious researcher looking for your next challenge?

Do you have an established background in Structural Molecular Biology?

Do you want to further your career in one of the UKs leading research intensive Universities?

The 203 kDa b-barrel Assembly Machinery (BAM) complex of Gram negative bacteria is an integral membrane protein that is required for the folding and insertion of outer membrane proteins (OMPs) and hence is essential for cell viability. Despite this central importance, how BAM folds and inserts the multitude of different OMP sequences that comprise the OM, and how this is able to occur efficiently in the crowded OM in the absence of an obvious source of energy such as ATP or a proton gradient, remain unclear. We are looking for an outstanding postdoctoral research fellow to join an MRC-funded team investigating the mechanism of action of the BAM complex using biochemistry, biophysics and structural biology.

This post will use molecular biology and structural biology techniques to probe the structure and function of the BAM complex. Successful execution of this MRC-funded programme grant will thus result in a new molecular understanding of this fascinating complex that is vital for bacterial life.

You will be based in the laboratory of Professors Sheena Radford and Neil Ranson at the University of Leeds and will work closely with other members of the membrane protein folding team. You should have a PhD (or be close to completion) in Structural Biology, Biochemistry, Biophysics or a related discipline, with experience of using either biophysical techniques and/or analysis of membrane protein structure and function.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.

To explore the post further or for any queries you may have, please contact:

StaffID=NAR">Neil Ranson , Professor of Structural Molecular Biology



StaffID=SER">Sheena Radford , Astbury Professor of Biophysics


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