Senior Scientist, Biophysical Chemistry

Chesterfield, Missouri
Feb 18, 2021
Feb 25, 2021
Jobseeker Type
Organization Type
Full Time

Biophysical chemist with objectives to contribute the development of life-saving medicines and to collaborate with fellow pharmaceutical scientists in supporting bioprocess development and product characterization by applying various biophysical techniques, such as advanced spectroscopy, separation techniques, electron microscopy, etc.

  • Apply various biophysical techniquesin characterizing proteins, nucleic acids, polysaccharides, synthetic polymers, viral capsids, nanoparticles, small molecule metabolites, etc. to support understanding the biotherapeutic products and bioprocess development
  • Develop and explore new applications and emerging technology in areas such as advanced molecular spectroscopy, state-of-art molecular separation techniques , electron microscopy, etc.tofurther advance in depthcharacterization of product quality attributes.
  • Participate in project teams and collaborate with colleagues from different functional lines to provide characterization support to advance portfolio.
  • Providehigh quality analytical resultsfor regulatory filing and participate in composing regulatory documents.
  • Mentor and coach junior scientists.

  • PhD in physical biochemistry, analytical biochemistry, biochemistry, chemistry, or relate field, with 0-3 years of post-doctoral or industrial experience in working with biological molecules by using a variety of biophysical tools.
  • Strong skills and experience in NMR spectroscopy, analytical ultracentrifugation, electron microscopy, CD spectroscopy and fluorescence spectroscopyare required.

  • Skills and knowledge in other molecular spectroscopy techniques such asFTIRspectroscopy, light scattering spectroscopy, etc., is highly desired.
  • Familiarity about separation technology including liquid chromatography, field flow fractionation, etc. is also desired.
  • Knowledge in polymer science, pharmaceutical sciences, statistical analysis, structural biology and molecular modeling will be considered.
  • Knowledge in mass spectrometry, biological assays and other general analytical techniques is also desired.
  • Experience in computer skills is helpful, including using MATLAB, Origin, Sigmaplot, etc.

  • Limited travel

Other Job Details:
  • Last Date to Apply for Job: March 3, 2021
  • Eligible for Relocation Package: YES
  • Eligible for Employee Referral Bonus: YES


Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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