Cell Biologist, Genomic Assay Development

Employer
GSK
Location
Collegeville, Pennsylvania
Salary
Competitive
Posted
Feb 24, 2021
Closes
Feb 27, 2021
Ref
536240
Jobseeker Type
Professional
Organization Type
Corporate
GlaxoSmithKline is looking for a highly motivated and creative Cell Biologist to join the department of Screening, Profiling & Mechanistic Biology (SPMB) at GSK's research facility in Upper Providence, Pennsylvania. The primary responsibility of the SPMB department is to deliver high quality, biologically relevant pre-clinical leads for all GSK therapeutic areas, by employing a combination of scientific tools and methodologies, including but not limited to assay development, high throughput screening, compound profiling, and mechanism of action studies.

As a Cell Biologist in SPMB, your role would be to identify, develop, and implement high-throughput assay systems. Potential platforms include transcriptomic, genomic, metabolomic, and proteomic readouts. Applicants should have strong cell biology abilities, particularly with primary cells, and background in bioinformatics.

The successful candidate will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists with expertise in various disciplines. The successful candidate will design, develop and execute trans-omic methodologies to enable new capabilities to implement a broader strategy to support and guide drug discovery process in multiple disease areas within GSK.

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:
  • PhD in biomedical/biological sciences, pharmacolgy, computational biology or related discipline with 5 years post-doc experience.
  • Experience in implementation of trans-omic methodologies.
  • Experience in primary cell/complex cell models
  • Experience in the analysis and integration of multi-omics data (e.g. transcriptomics, genomics, proteomics) for disease research.
  • Publication record in peer-reviewed journals.
  • Experience in a programming language (such as R or Python) for complex data analysis.


Preferred Qualifications:

If you have the following characteristics, it would be a plus:
  • Skills to collect, integrate, mine and analyze complex biological data and translate them into testable hypotheses.
  • Knowledge of and experience with common bioinformatics databases, resources and tools.
  • Experience with data and/or results from large scale differential gene expression analysis of compound and genetic perturbations.
  • Familiarity with machine learning approaches and their application to genetics/genomics.
  • Ability to work independently and in team-based settings.
  • Strong verbal and written communication skills to communicate complex concepts and computational analyses clearly to influence diverse audiences.


Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.

*LI-GSK

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