Scientist - Biology (non-PhD)

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Pfizer Vaccines Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into vaccines that matter most. You will apply cutting edge design and process development capabilities to accelerate and bring the best in class vaccines to patients around the world.

What You Will Achieve

As a Scientist in the Molecular Biology team embedded in Bacterial Vaccines and Technology, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be part of a team that is addressing the critical task of rejuvenating our pipeline with innovative and critical vaccine programs in the years to come. The Molecular Biology team plays a key role in early antigen development for vaccines and assay development: focusing on cloning, expression, purification and preliminary antigen characterization as well as addressing research questions critical to progression of vaccine programs. With your deep knowledge in molecular biology, bacterial and viral pathogens, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

• Execute experiments to further project goals
• Contribute original ideas and actively participate in planning projects
• Multitasking projects and demonstrating problem solving skills in the planning and execution of objectives
• Have a willingness to learn new skills and adapt to changing priorities
• Interpret and summarize experimental data. Participate in the evaluation of new methods or technologies
• Present experimental results at group meetings, project meetings, and department meetings, as required. Write research reports
• Maintain laboratory notebook in a detailed and descriptive manner. Keep current in entries into the strains and vector databases
• Contribute to achievement of goals of the team and influence at the work group/project team level
• Apply technical skills and functional knowledge to projects/ assignments within own work group/ project team independently and proactively
• Comply with all safety training and good laboratory practices

Qualifications

Must-Have

• B.S./M.S. degree (NOTE: non-Ph.D.) in Molecular Biology, Microbiology, or a related discipline
• Minimum of 5 years of research experience post-graduation
• Minimum of 5 years of hands-on experience with plasmid cloning and protein expression in E. coli
• Demonstrated knowledge of bacterial and viral pathogens including genetic knockout construction
• Ability to work independently on molecular biology and protein expression projects
• Proficiency in general microbiology and molecular biology techniques (Nucleic acid extraction and handling, PCR, Gibson assembly, restriction enzyme-based cloning, DNA sequencing)
• Proficient in the design and construction of complex plasmid or viral vectors
• Experienced user of cloning software (Vector NTI, DNAStar, Geneious)
• Demonstrated skills in bacterial or viral protein expression systems ( E. coli, mammalian cell handling and transfections, baculovirus / insect cell expression systems, Pichia pastoris )
• Competent in protein analysis (SDS-PAGE, Western blot, quantitation by UV or colorimetric methods)
• Hands-on skills in small scale protein purification approaches (e.g. nickel or GST affinity purification)
• Ability to troubleshoot cloning, expression or purification challenges
• Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, strong motivation with a dedicated work ethic
• Proficiency with Microsoft Office applications and relevant scientific software, including graphing/statistical analysis tools is expected
• Excellent verbal and written communication skills

Nice-to-Have

• Hands-on experience with ÄKTA purification systems
• Familiarity with Octet Bio-Layer Interferometry and/or ELISA assays
• Experience with RNA isolation, qRT-PCR and qPCR assay design and development
• Experience with Illumina sequencing platforms and data analysis

To apply, please submit a resume accompanied by a cover letter

PHYSICAL/MENTAL REQUIREMENTS

Sitting, standing, walking, light lifting (

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Travel to regional, national and international meetings. Adherence to safe work practices and procedures required.

Other Job Details:

• Eligible for employee referral programs: YES
• Eligible for relocation support: YES

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Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development