Scientist, Early Bioprocess Development

Pearl River, New York
Apr 05, 2021
Apr 10, 2021
Jobseeker Type
Organization Type
Full Time

The incumbent will develop and perform glycoconjugate processes for manufacturing carbohydrate-based vaccines. Primary duties include; development and optimization of conjugation methods, purification and analysis of glycoconjugates. The individual will become a key contributor towards the early development and scale up of glycoconjugate vaccines. Careful documentation of work and presentation of data is required. All work is to be done in a compliant manner according to SOP guidelines and cGMP/GLP regulations, where applicable.

  • Develop, optimize and scale-up conjugation process for glycoconjugate vaccine candidates.
  • Plan and execute experiments for conjugate vaccine candidates.
  • Presents periodic status update, discuss problems and proposed solutions in discussion with group members. Offer insights based on experience to group members to help solve problems.
  • Continuously evaluate each process and technique to determine if it is robust, appropriate and scalable. If an operation has shortcomings or can be improved, uses expertise or work with senior group members to advance objectives.
  • Collaborate with colleagues within Early Bioprocess Development and other Vaccine Research and Development organizations.
  • Participate in the technology transfer of developed process to the clinical manufacturing site, both internally and externally, and provide the technical support as needed.
  • Fully document laboratory experiments in electronic notebook in a timely and compliant manner and prepare technical reports as needed.

  • M.S. degree in Chemistry/ Biochemistry with minimum 3 years experience in carbohydrate or related field or B.S. degree in Chemistry/ Biochemistry with minimum 5 years related experience in carbohydrate or related field.
  • Strong background in organic chemistry is required.
  • Experience in glycoconjugate process development, scale-up, purification and glycoconjugate analysis.
  • Knowledge and ability to design, plan, and execute conjugation and purification activities.
  • These should also include the ability to operate and maintain relevant instruments, resolve technical problems related to instruments, and execution of analytical methods.
  • Independently analyze and provide conclusions regarding experimental data generated.
  • Hands on experience with various analytical techniques such as HPLC, SEC-MALS, UV-Vis, NMR and other routine lab instruments.
  • Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable.
  • Strong verbal and written communication skills are required.
  • Experience with documentation of laboratory notebook in an electronic format.

Other Job Details:
  • Last Date to Apply for Job: April 9, 2021
  • Eligible for Employee Referral Bonus: YES

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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