PhD student position in 'Bone marrow niche engineering'

Employer
University of Basel
Location
Basel, Switzerland
Posted
Apr 18, 2021
Closes
May 16, 2021
Ref
165582
Organization Type
University and College
Hours
Full Time
The Tissue Engineering Group at the Department of Biomedicine of the University Hospital Basel & University of Basel in Switzerland is currently seeking for a highly motivated PhD candidate to work on the development of biomimetic human bone marrow stem cell niches to model fundamental and clinical aspects of healthy and malignant hematopoiesis.

Your position
In the context of a National Centre of Competence in Research (NCCRs) program funded by the Swiss National Science Foundation, the PhD candidate is expected to be responsible for a challenging project at the interface between Hematopoietic Stem Cell research and Tissue Engineering. The highly interdisciplinary study aims at investigating the regulatory function of vascular components in hematopoietic stem cell niches, exploiting engineered human organotypic models. The project will combine cutting-edge components, such as endothelial cells derived from induced Pluripotent Stem Cells (collaboration with Prof. B. Treutlein at the ETHZ, D-BSSE), perfusion bioreactors for 3D culture and single-cell analytical techniques.

Your profile
  • A Master degree in Biomedical/Life Sciences or equivalent
  • Experience in cellular/molecular biology and cell culture techniques (mandatory)
  • Familiarity with routine cellular/molecular biology techniques (DNA/RNA/Protein extraction, Q-PCR, flow cytometry, microscopy/imaging) (desirable)
  • Experience in stem cell research and/or tissue engineering (as a plus).
  • Excellent communication, writing and presentation skills
  • Outstanding motivation and capacity to work in interdisciplinary teams


We offer
The interdisciplinary Tissue Engineering Group in Basel, directed by Prof. Ivan Martin, generally aims at understanding mechanisms governing tissue regeneration and to translate this knowledge into innovative clinical approaches for cartilage, bone and bone marrow healing. In this environment, we offer you to take part on an exciting and collaborative project.

The Department of Biomedicine offers an excellent research environment with world-class research facilities, ideal for building a scientific career. The city of Basel, located on the borders of both France and Germany, is one of leading pharmaceutical and biotechnological centers in the world. For more information on the research group, please visit

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