Clinical Trials Laboratory Technician

PROSECO (A UK Multicentre Prospective Observational Study Evaluating COVID-19 Vaccine Immune Responses in Lymphoid Cancer)

University of Southampton, Faculty of Medicine, Cancer Sciences Unit, Experimental Cancer Medicine Centre

We are looking to appoint a highly motivated, full-time Laboratory Technician to support PROSECO, a clinical trial funded by the Vaccine Blood Cancer Research Consortium. PROSECO is a UK multicentre observational study aimed at evaluating the robustness and persistence of immune responses in patients with lymphoid malignancies after COVID-19 vaccination. Your role will be to support the Southampton Experimental Cancer Medicine Centre in undertaking the laboratory work associated with this study (peripheral blood mononuclear cell isolation, T, B, NK cell analysis using multicolour flow cytometry and T-cell ELISPOT), and the analysis of this data. It is highly likely that the successful applicant will have an opportunity to co-author a publication from this study.

You will have relevant laboratory experience, display an ability to work flexibly and out-of-hours when necessary and to meet tight deadlines associated with this trial.

The post holder will be primarily based in the WISH laboratory at the University Hospital Southampton. You will be required to comply with meticulous record-keeping and database management for all processes undertaken, as well as fully comply with requirements of GCP for laboratories. Training will be provided where necessary. There may be also the opportunity to work with other team members to carry out immunomonitoring assays in other clinical trial samples (e.g. flow cytometry, ELISA and immunohistochemistry assays).

You will require a good understanding of the current health and safety regulations and must undergo occupational health clearance for the job role.

The appointment is a full time, 12 months fixed-term in the first instance, with a potential for a further 6 months' extension depending on performance and the progress of the trial.

For an informal discussion or to arrange a visit please contact Dr Sean Lim ( s.h.lim@soton.ac.uk ) or Dr Debora Joseph-Pietras ( d.joseph-pietras@soton.ac.uk ).

At the University of Southampton we promote equality and value diversity.

We aim to be an equal opportunities employer and welcome applications from all sections of the community.