Senior Scientist - LC-MS Protein Characterization

Employer
GSK
Location
Collegeville, Pennsylvania
Salary
Competitive
Posted
Apr 14, 2021
Closes
May 07, 2021
Ref
545458
Jobseeker Type
Professional
Organization Type
Corporate
The candidate will be primarily responsible for conducting mass spec-based experiments (e.g. LC-MS and LC-MS/MS) and perform the corresponding data analysis for the characterization of therapeutic proteins. The candidate may be expected to develop other analytical and/or biochemical methods to further understand the structure-function relationship of proteins, while supporting biopharmaceutical development from FTIH through commercial.

The mass spec group is well equipped with modern instrumentation including Exploris 480, Eclipse Tribrid, Q Exactive Plus, Orbitrap Fusion Tribrid, Synapt G2S with both H/DX and IM, Xevo G2-XS, Orbitrap XL, NanoUPLC, UHPLC and other supporting instrumentation and associated data analysis software.

Why you?

Basic Qualifications:

  • B.S. with 6+ years of experience or M.S. with at least 2 years of experience in biotech or pharmaceutical industry
  • Hands-on experience in protein characterization and data analysis using mass spectrometry, including intact. reduced LC-MS and peptide mapping LC-MS/MS workflows
  • Hands-on experience and troubleshooting HPLC/UPLC
  • Preferred Qualifications:
  • Scientific and working knowledge in protein structure and function
  • Scientific and working knowledge in glycosylation of proteins and/or glycomics analysis
  • Experience in biopharmaceutical development, supporting FTIH through commercial
  • Motivated with excellent communication skills, both written and verbal. Candidate should be an instinctive team player with excellent people skills.

    Why GSK?

    Our values and expectationsare at the heart of everything we do and form an important part of our culture.

    These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.



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