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Research Associate - control of glial neuroinflammatory signalling in Parkinson's

Employer
University of Bristol
Location
Bristol, United Kingdom
Salary
£33,797 - annum
Closing date
Jun 27, 2021

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The role

A Postdoctoral position is available in the lab of Dr Jon Lane to investigate the control of glial neuroinflammatory signalling in Parkinson's, and how inflammation influences dopaminergic neuronal health in vitro.

What will you be doing?

Neuroinflammation proceeds clinical symptoms of Parkinson's, highlighting its potential as a predictive biomarker and therapeutic target. You will model neuroinflammatory signalling in cell culture, using human iPSC-derived microglia and mid-brain astrocytes. By establishing tripartite co-cultures and/or by media transfer, you will characterise the neuroinflammatory signals that contribute to ventral midbrain dopaminergic neuronal stress in Parkinson's.

You should apply if

We are seeking to recruit a talented, highly motivated individual, with a strong record of productivity, holding (or soon to complete) a PhD in cell biology or a related discipline. Successful candidates will be able to demonstrate expertise in human iPSC cell culture and/or neuronal or glial cell biology.

We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.

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