Research Fellow in Somatosensory Neuroscience

Employer
University of Leeds
Location
Leeds, United Kingdom
Salary
£33,797 to £40,322 p.a.
Posted
Jun 08, 2021
Closes
Jul 04, 2021
Ref
168907
Organization Type
University and College
Hours
Full Time
Are you an ambitious researcher looking for your next challenge?

Do you have an established background in neuroscience?

Do you want to further your career in one of the UKs leading research intensive Universities?

We are looking for an enthusiastic scientist to join the team lead by Prof Nikita Gamper on an MRC-funded project focusing on molecular mechanisms of pain. This project builds on the group's recent discovery that spinal somatosensory ganglia actively filter peripherally-born action potentials traveling along sensory nerves to the CNS. Our ultimate goal is to unravel basic principles of ganglionic filtering in order to develop new or improve existing therapeutic interventions. We will use tissue clearing and light sheet microscopy in combination with genetic labelling of sensory neurons with defined and distinct sensory modalities to obtain accurate morphometry of their somata and axons. This will be further supplemented by generating a database of biophysical parameters of different fiber types obtained by electrophysiology. These measurements will generate parameters for realistic computational modelling of signal propagation in different types of afferent fibers. We will then use mouse neuropathic pain models in combination with in vivo electrophysiological recordings to directly measure changes in filtering efficiency in neuropathic animals.

You should have A PhD (or close to completion) in neuroscience or a closely allied discipline, with experience in electrophysiology, somatosensory physiology, fluorescence imaging, and animal pain models.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.

To explore the post further or for any queries you may have, please contact:

Professor Nikita Gamper

Tel: +44 (0)113 343 7923, Email: n.gamper@leeds.ac.uk (preferential contact method)

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