Postdoctoral Position in Development of Artificial Cells by using Microfluidics

Employer
University of Basel
Location
Basel, Switzerland
Posted
Jun 08, 2021
Closes
Jul 07, 2021
Ref
168920
Organization Type
University and College
Hours
Full Time
We invite candidates to submit applications for a PostDoc position in a joint project between the nanoscience-oriented physical chemistry groups of Professor Wolfgang Meier and Cornelia Palivan, Department of Chemistry, at the University of Basel, Switzerland. The position is for one year, with possible prolongation up to two years.

Your position

The overall aim of this project is the development of artificial cells based on combination of active compounds (enzymes, membrane proteins, mimics) and synthetic microcompartments generated by microfluidics. A particularly important part of the project will intend to evaluate the interaction between the synthetic compartments and specific biomolecules, as a key element for the stability
and functionality of the artificial cells. In addition, new design of the microfluidics chips will support assemblies with desired properties and allow in situ structural characterization of the artificial cells as a prerequisite for their therapeutics and diagnostics applications.

This is an interdisciplinary project from which you will gain valuable experience in the domain of nanoscience, physical chemistry, biochemistry and microfluidics approaches. Your role will be to adapt or design new microfluidics chips for production of stable synthetic compartments and combination of thereof with biomolecules, to control their interaction and functionality for efficient generation and scale-up of artificial cells. More information on the topics of the groups in which you
will be working can be found at http://www.chemie.unibas.ch/~meier/ andhttp://www.chemie.unibas.ch/~palivan/ .

Your profile

  • you will ideally have a PhD in chemistry, biochemistry or material science;
  • experience in microfluidics set-up is a must;
  • experience in protein biochemistry techniques (e.g. gel electrophoresis, protein purification) is a must;
  • high records of publications in internationally refereed scientific journals
  • proficiency in English; German is an advantage.

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