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Principal Scientist

Employer
MPI Research
Location
West Side, MA
Closing date
Aug 2, 2021

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Sector
Science
Organization Type
Corporate
Job Summary

We are seeking a Principal Scientist 3 for our Discovery site located Worcester, MA

We are seeking a highly-motivated individual with extensive hands-on experience in developing large molecule bioanalytical assays by LC-MS/MS to join our discovery bioanalytical team. The scientist will be responsible for method development and execution of quantitative assays, critical review of data, mentoring junior staff, and maintaining analytical equipment. Individuals in this role will also serve as primary point of communication with the clients. The scientist is expected to work independently to deliver high-quality non-GLP data in a fast-paced environment.

The successful candidate in this position will have:

A solid understanding of analytical approaches for the quantitation of siRNA, ASOs, proteins, antibodies and other complex modalities.
Experience in extraction and analysis of biological samples, data generation, review of results and scientific presentation
Excellent scientific communication and interpersonal skills
Demonstrated ability to work collaboratively in a team environment with colleagues at various levels
Attention to detail and the ability to critically analyze and verify data prior to data release
Experience in large molecule LC-MS bioanalysis with an emphasis on siRNA, ASOs, proteins, antibodies and complex modalities.
Exceptional method development and assay troubleshooting skills
Technical proficiency in operation of analytical instrumentation including chromatography and mass spectrometry systems (HPLC: Agilent, Waters Acquity, Thermo Vanquish; Mass Spectrometer: Sciex 5500 & 6500, Thermo QE HRMS)
Previous experience leading a team is preferred as this position will include responsibility for overseeing scientific growth and development of junior staff

The following are minimum qualifications related to the Principal Scientist 3 position:

Education: Bachelors degree (B.S./B.A.) or equivalent in a scientific related discipline. Related Masters degree (M.S./M.A.) or Ph.D. preferred.
Experience: Minimum of 9 years related experience in the contract research, academic, or pharmaceutical industry.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Certification/Licensure: Certification as appropriate for specialty preferred.
Other: Full understanding of regulatory requirements of study types assigned, as well as Testing Facility SOPs, as appropriate. Knowledge of applicable international guidelines for all types of studies. Demonstrate leadership skills as they pertain to intra- and interdepartmental initiatives, Sponsor interactions, and business development. Effective written and verbal communication skills. Ability to handle multiple projects, prioritize work and meet deadlines. Proficiency in the use of standard software including Microsoft® Excel, Word, PowerPoint, etc. and analytical instrumentation software.

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