Staff Scientist - Pediatric CAR T Cell Therapies

This Project Development Scientist position will be part of the Clinical and Translational Project Development Core supporting project management for a California Institute of Regenerative Medicine (CIRM)-funded clinical trial, grant reporting, future grant submissions and manuscript writing. This Project Development Scientist will be affiliated with a Phase I Clinical Trial led by Dr. Leo D. Wang, focusing on chimeric antigen receptor (CAR) T cell therapies in pediatric populations. S/he will work closely with program-associated laboratory and clinical researchers, regulatory staff and biostatisticians to shepherd projects from conception to grant funding, to clinical trial, to manuscript.

Responsibilities Include:

CIRM Project Management: Scientist will manage timelines, all site visits, and quarterly progress reporting for a CIRM CLIN 2 grant funding an ongoing clinical trial of CAR T cells in pediatric neurooncology patients.
Develop In-depth Knowledge of Immunotherapy Program Research Goals and Areas of Emphasis: Scientists are expected to become well-versed in the terminology, biology and treatments associated with the Immunotherapy Center and Cellular Therapies program. Scientists will attend Immunotherapy Center Disease Team meetings, Pediatrics Disease Team meetings, Wang laboratory pre-clinical research data meetings, and relevant seminars and conferences to gain a thorough familiarity with the ongoing research interests of the Immunotherapy Center.
Project Design and Grant Writing: Scientists will assist and advise in design and preparation of new projects for funding as well as managing the logistics of grant submission. They will help match investigators to appropriate grant opportunities throughout the stages of project and career development. They will edit/write portions of the grant text and frame the project as appropriate for the specific application. They will also assist in preparing grant progress reports for grants that have been awarded.
Clinical Protocol Writing and Submission: Scientists will work with the protocol design team (laboratory and clinical investigators, biostatisticians, research nurses, investigational pharmacists) on clinical trial design and protocol preparation for Immunotherapy Center investigator-initiated early-phase clinical trials. Scientists will interface with Research Support Services to develop consent forms. For translational projects involving a City of Hope-held Investigational New Drug Application (IND), they will provide and review text and figures for IND submission.
Manuscript Writing and Public Access Compliance: Scientists will advise and assist investigators with interpretation and presentation of clinical / translational data for publication and edit/write portions of the manuscript text. They will also ensure that the appropriate funding agencies and the City of Hope Comprehensive Cancer Center Support Grant are acknowledged, and that NIH-funded manuscripts are archived in PubMed Central.

Basic education, experience and skills required for consideration:

PhD in the biological/chemical sciences with at least 2 years' experience / Master's degree with at least 5 years of experience / Bachelor's with at least 8 years of experience in scientific writing, clinical study management, or clinical trial regulatory experience in a healthcare/research/academic environment.

Preferred education, experience, and skills:

NIH or DOD research grant writing (R01 level, not post-doctoral fellowships), involvement with human observational or therapeutic studies, protocol design/writing for human sample, observational/retrospective or therapeutic studies, translational project management.
Familiarity with data analysis techniques, graphing methods, and interpretation of laboratory and clinical data.