Postdoctoral Fellow - Cancer Genetics/Epigenetics

Seeking a Postdoctoral to join the lab of Dr. Chun-Wei (David) Chen in Systems Biology focused on the epigenetic mechanisms underlying the therapeutic resistance in cancers. This laboratory is skilled in high-throughput CRISPR genetic screens for de novo therapeutic target discovery. They also utilize next-generation sequencing (NGS) for epigenomic and transcriptomic analyses (ChIPseq, ATACseq, RNAseq, etc.), and the patient-derived xenograft (PDX) models for in vivo therapeutic efficacy assessments. In addition, Dr. Chen's laboratory is involved in cutting-edge technology development including high-density CRISPR protein scan, precision epigenome editing, and single-cell CRISPR/RNA-seq. The lab is well funded by several NIH (R37 MERIT, R01s, U54) and foundation (ASH, LLS, ALSF, COSF, SU2C-CRUK) awards.

Basic education, experience and skills required for consideration:

A Ph.D. degree in biomedical sciences, structural biology, computational biology or bioinformatics (required).
Good oral and written communication skills in English (required).
Experience in cell biology, molecular cloning, or animal model studies (highly preferred).
Experience in transcriptomic, proteomic, epigenetic, molecular dynamic, or protein structural data analysis (highly preferred).
Experience in protein purification, compound screen, protein/protein or protein/compound interaction (highly preferred).
Experience in R, Python, Perl, UNIX/LINUX, etc. (highly preferred).