Postdoctoral Fellow - Diabetes Complications and Metabolism

A Postdoctoral Fellow position is immediately available in the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and Metabolism Research Institute within Beckman Research Institute of City of Hope, CA. The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, with a goal to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions. We have a unique research program in deciphering the mechanistic underpinnings of circadian clock control in metabolic tissue development, growth and functional capacity, specifically in skeletal muscle and adipose tissue.

We are seeking a highly motivated postdoctoral fellow with strong enthusiasm for metabolic disease or stem cell research to study molecular signaling mechanisms underlying circadian clock function in skeletal muscle and adipose tissue. Candidates with strong training in cell biology, molecular biology and biochemical techniques are preferred, and prior experience with animal models is a plus. Utilizing biochemical and molecular biology approaches combined with genetic animal models, specific research directions in the lab include: 1) genetic and epigenetic signaling networks mediating circadian clock nutrient-sensing function in adipose tissue and skeletal muscle; 2) circadian clock regulation of skeletal muscle growth and metabolism; and 3) novel signaling mechanisms in core circadian clock regulation.

The candidate should be self-motivated, with a proven track record of publications and strong interest to pursue metabolic disease research. Expertise in biochemistry, cell biology and animal physiology are preferred. Technical skills in metabolic, epigenetics and stem cell research are a plus.

Basic education, experience and skills required for consideration:

PhD in Molecular, Cellular or Developmental Biology.
Proficiency with biochemical techniques, molecular biology skills and cell culture systems.
Experience with in vivo animal model research preferred.
Experience with epigenetics research and bioinformatics analysis a plus.
Highly motivated with strong interest in metabolic disease research.
Strong work ethic and ability to work effectively in a team.