Associate Scientist, Protein Therapeutics

Gilead Sciences
Belmont, CA
Closing date
Sep 30, 2021

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Job Description
Gilead Sciences currently has an excellent opportunity for an associate scientist to join our protein chemistry group for small molecule drug discovery program. This person will work with a wide range of therapeutic areas in a highly productive environment. He or she will be responsible for generating recombinant proteins and collaborating with enzymology, high-throughput screening, and structural chemistry groups to support assay development, mechanism of action, and structural studies. The successful candidate should be self-driven, independent, and expected to work in a collaborative setting.

Functions and Responsibilities

Independently design constructs and execute purification of protein targets across therapeutic areas using E coli, and Baculoviral expression systems
Perform protein quality control experiments using techniques such as SDS-PAGE, Western blot, SEC-MAL, and HPLC
Trouble shoot protein purification techniques using FPLC
Encouraged to explore and innovate new techniques for protein sciences
Participate in group and team meetings and present data
Ability to interpret and draw conclusion from data and eager to work in a fast-paced environment
Maintain knowledge of the advancement in the relevant scientific field
Strong organization with respect to documentation of electronic notebook, report writing, and communication skills are essential
Education and Skills

BS or MS in protein biochemistry, biology or related field
5-8 plus years of experience in protein purification and characterization
Experience on structure-based design and engineering of protein targets
Strong familiarity with the use of AKTA instruments and practical experience on protein purification techniques such as affinity, ion-exchange, and size-exclusion chromatography
Knowledge on mass spectrometry and cell culture work is a plus
Biotechnology/pharmaceutical industry experience is preferred
Job title will be commensurate with experience

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