Director, Mammalian Genomic Engineering Resource Center

3 days left

California Institute of Technology
Pasadena, CA
Sep 16, 2021
Sep 21, 2021
Organization Type
Director, Mammalian Genomic Engineering Resource Center


Job Category: Fulltime Regular
Exempt Overtime Eligible: Exempt
Benefits Eligible: Benefit Based

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.

Job Summary
The Division of Biology and Biological Engineering (BBE) at Caltech is seeking a Director for our new Mammalian Genome Engineering Resource Center (MGERC).

The MGERC is a service facility that supports the research activities of faculty across the BBE Division. The Director is a staff position who will report to a responsible faculty member and to a faculty steering committee that provides oversight.

Job Duties
Genome Engineering

The successful candidate will participate in advances in the genome engineering to establish a Mammalian Genome Resource Center at Caltech. They would establish current state-of-the-art techniques for the field and be able to continuously update genome engineering technology in the Resource Center. To this end, they would be expected to attend conferences, follow research literature, and discuss and establish new approaches with faculty.

The Director will use their personal skills in transgenesis, oocyte and embryo injection, electroporation, embryo micro-manipulation and transfer, ES cell derivation, cloning, and CRISPR technology. They will interact with faculty members to devise appropriate experimental strategies.

In addition to mice, the Director would, with time, develop experimental approaches applicable to other mammalian species.

Management and Leadership

The Director will train and supervise staff members working in the Resource Center to the common goal of maintaining the Center at the forefront of developments. They will contribute to making decisions on hiring, promotions, salary changes, performance evaluations, and terminations.

Animal Care and Well-Being

The Director will plan, oversee, and coordinate day-to-day operations and administration of the Resource Center. Part of their time will be spent in Caltech's AAALAC accredited animal facilities. Policies regarding maintenance of the integrity of the rodent facilities, with regard to pathological status of animals, have been established by the Office of Laboratory Animal Resources (OLAR). They will ensure that all facility operating procedures meet the requirements of OLAR and Federal and State regulations governing the care and treatment of animals in research. They will ensure that staff provide a level of technical support to investigators in assisting with experimental work and provision of data pertaining to it. The Director will organize re-derivation and cryopreservation programs as needed and train and educate researchers in proper laboratory animal procedures and activity in the field of transgenic technology.

Budgeting and Administration

Collaborating with Division Administration, the Director will manage and administer a charge-back system for services; participate in choosing and purchasing equipment in the development of new facilities.

Basic Qualifications
* Masters Degree in developmental biology or related field
* Experience and knowledge of methods for transgenesis, oocyte and embryo injection, electroporation, embryo micro-manipulation and transfer, ES cell derivation, cloning, molecular biology, and CRISPR mutagenesis.
* Experience in management at either research project or facility level.
* Ability to develop and maintain housekeeping, safety, and establish procedures for maintaining pathogen-free rodents.
* Knowledge and understanding of Federal and State laws, regulations, guidelines, and standards for the treatment of laboratory animals.
* Strong interpersonal and communication skills and the ability to effectively collaborate with Caltech research groups.
* Ability to supervise and train assigned staff including organizing and scheduling work assignments.
* Budget planning and accounting skills.

Preferred Qualifications
* Ph.D. in mammalian developmental biology or related field with postdoctoral experience.

Required Documents
* Resume

To be considered for this position please visit our web site and apply on line at the following link:

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.


Similar jobs

More searches like this

Similar jobs