Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers. Our group performs cutting-edge research in GI oncology, is very productive and publishes in high-impact journals such as Gastroenterology, JNCI, Clinical Cancer Research, Nature Communications, Annals of Surgery etc.
Key Responsibilities include:
Devise, plan, document and advance basic science and translational projects in the area of precision oncology of gastrointestinal cancers.
Generate data for grant applications and prepare manuscripts for publication.
Work in close collaboration with other team members and external collaborators, including presentation of progress internally or externally.
Train and supervise technical staff.
Basic education, experience and skills required for consideration:
Recent PhD, MD or MD/PhD, with a strong background and profound knowledge in the field of oncology, cancer biology, immunology or immunotherapy.
Ability to work in a fast-paced research environment and manage multiple projects and collaborations.
Previous experience in working with human specimens and development of novel, innovative cancer biomarkers.
Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications.
Strong team player with excellent communication skills and fluency in English, both spoken and written.
Commitment to the program for at least two-three years.