Postdoctoral Research Scientist Pathology & Cell Biology - Gardner Lab
Officer of Research
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A position is available, beginning September 1, 2021, in the Department of Pathology and Cell Biology at the Columbia University Medical Center. The position will have an integrated focus on fundamental mechanisms of cell biology and gene regulation including basic mechanisms of epigenetic regulation and enhancer control, and their linkage to pathways that drive the developing tumor fitness in breast cancer, and how the elucidation of these pathways can be leveraged to further diagnosis, treatment, and prevention of breast cancer. An essential component of these efforts includes developing omic perspectives that integrate next-generation sequencing with genomics, transcriptomics, epigenomics, proteomics, metabolomics, and patient sample image analysis. The projects will be supported by access to an established diverse cohort of breast cancer patient samples with deep next-generation molecular genomic characterization for both gene and pathway discovery and computational image analysis of breast cancer in the diagnosis, treatment, and prevention, and treatment of cancer.
The CUMC Dept of Pathology and Cell Biology a world-class group of investigators that is one of the top-ranked Pathology Departments in the country that provides a supportive and collegial environment with extensive opportunities for professional development and advancement to top tier careers in academia and industry. Its location on the Upper West Side of Manhattan enables access to the multiple sites of interest, culture, and lifestyle in New York City.
Ph.D. or M.D. equivalent in areas of biochemistry, cancer biology, cell & molecular biology, or related field. A proven track record of publication in epigenomics, molecular biology, or stem cell biology with a combined strong interest and focus on the basic mechanism of biology and their translational implications for disease incidence and progression is preferred. Expertise in the performance of tissue culture and cell-based cell and tissue analysis is required. Familiarity with bioinformatics approaches and technologies in manipulating and interpreting deep sequencing data would be a significant advantage. We are looking for an individual with a strong desire to work on fundamental research questions in cancer, chromatin biology, and their influence on the tumor microenvironment. A background in immunology is desirable but not required. Those candidates with proven research experience and a history of an ability to independently drive a project forward in an interactive environment, with a willingness to provide mentorship to junior lab members, are highly desirable. Prior experience in patient-derived xenografts approaches and technology (PDX) would be very competitive.
Those interested in applying are encouraged to submit a summary of research accomplishments and future research interests and plans; a current CV; and at least two references.
Equal Employment Opportunity Statement
Columbia University is an Equal Opportunity Employer / Disability / Veteran