Research Associate 1 MS

Yale University
West Haven, CT
Sep 12, 2021
Sep 15, 2021
Organization Type
Essential Duties

1. Recommends the design and implementation of procedures and protocols under the direction of a higher-level authority. 2. Investigates, analyzes, and reaches preliminary scientific conclusions related to research planning 3. Ensures data results are compiled, analyzed, and presented properly. 4. Analyzes, develops and interprets scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports. 5. Performs independent research and laboratory techniques and participates in experimental research planning. 6. Interacts with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory. 7. Interacts with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and to keep abreast of product information and developments. 8. May perform other duties as assigned.

Required Education and Experience

Master's Degree in a scientific discipline and one year experience or an equivalent combination of education and experience.

Background Check Requirements

All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. Please visit for additional information on the background check requirements and process.

Position Focus:

Under the general direction and supervision of the Research Associate II of the Yale Center for Genome Analysis (YCGA), this individual will supervise the library prep and sequence production sections. Additionally, they will lead library prep R&D efforts in protocol development, robotic implementation for the Precision Medicine Initiative as well as all updated equipment implementations and provide support for Covid19 sample processing. This position involves work to be performed in a core lab requiring attention to costs. Responsibilities will include the following and other duties as assigned:

Supervise the library prep and sequence productions sections and assign work to other team members to ensure efficient operations and workflow.

Interact with the Research Associate II and the Associate Director and/or Director of YCGA daily to coordinate and maintain sequencer and library prep schedule and staff project assignments.

Lead Library prep R&D protocol development as well as become subject matter expert on all library prep robotic implementations and new equipment. Train others on the equipment as needed. Maintain and update the robotics and equipment as required.

Establish Standard Operating Procedures and develop general policies regarding RNA-seq library prep and user prepared library QC.

Directly assist the Research Associate II in supervision of the staff and function, as needed, as the supervisor for sequencing and library preparation. Represent Research Associate II, as needed, with the Administrative Supervisor of the facility on all administrative issues including but not limited to staffing, temporary/casual usage, resolution of workflow and staff issues, performance management, scheduling, work rules, University policy and bargaining unit interpretation, etc.

Carry out library and flow cell prep production, maintain equipment, and perform other duties as required.

Troubleshoot and resolve library prep and sequencing instrument related issues with technical support.

Interpret and generate reports summarizing library prep and sequencing results. Communicate with investigators and collaborators. Provide technical assistance to the users.

Interact with various YCGA operation teams. Provide orientation and training to new lab personnel including instruction in laboratory protocols and providing information and practical assistance as required.

Help oversee and maintain the day-to-day operations of the lab.

Maintain and update information on the YCGA website.

Assist in the development of the future laboratory information management system (LIMS).

Perform literature searches to determine current trends in sequencing operation and remain pro-active in adapting appropriate protocols.

Assist with gathering information for grants and proposals and provide support with editing.

Preferred Education, Experience and Skills:

Experience in basic molecular biology techniques such as PCR, DNA/RNA extraction, and gel electrophoresis. Experience in various areas of sequencing workflow such as operation of Illumina NovaSeq instruments and RNA-seq library preparation for Illumina sequencing. Experience in a core lab setting with demonstrated customer service skills.

Posting Disclaimer

The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.

Affirmative Action Statement:

Yale University considers applicants for employment without regard to, and does not discriminate on the basis of, an individual's sex, race, color, religion, age, disability, status as a veteran, or national or ethnic origin; nor does Yale discriminate on the basis of sexual orientation or gender identity or expression. Title IX of the Education Amendments of 1972 protects people from sex discrimination in educational programs and activities at institutions that receive federal financial assistance. Questions regarding Title IX may be referred to the University's Title IX Coordinator, at, or to the U.S. Department of Education, Office for Civil Rights, 8th Floor, Five Post Office Square, Boston MA 02109-3921. Telephone: 617.289.0111, Fax: 617.289.0150, TDD: 800.877.8339, or Email:

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