Associate Data Analyst

Site Name: USA - Massachusetts - Cambridge Posted Date: Sep 7 2021 The Encoded Library Technologies (ELT) group at GSK operates at the leading edge of drug discovery where at any given point we are seeking affinity probes or starting points for medicinal chemistry for dozens of projects across the entire research portfolio. The ELT Platform includes a large collection of unique DNA-encoded libraries (DELs) and continually develops new DELs and new technologies for screening these libraries against multiple diverse protein targets of interest. This role will be a key contributor to the team that processes and analyzes ELT screening data to enable post selection chemistry decision making. The role will require demonstrated data science contributions from inception to delivery and a working knowledge of chemistry within a life science research setting. *For a review of ELT at GSK see: Arico-Muendel, C. C. From haystack to needle: finding value with DNA encoded library technology at GSK. MedChemComm 2016, DOI: 10. 1039/c6md00341a https://pubs.rsc.org/en/content/articlelanding/2016/md/c6md00341a Key Responsibilities include, but are not limited to: Accountable for scoping and building chemical structure and property analysis workflows that maximize impact for Encoded Library Technology data Prepare specialized visualizations of ELT data for team members, enabling downstream decision making for the Post-selection Chemistry group. Contribute to the exploration of new analysis methodologies as they apply to Encoded Library Technology and/or small molecule discovery associated data Contribute to documentation and training materials as part of full lifecycle management to ensure embedding in the scientific organization Improve current hit identification processing scripts Basic Qualifications: BS in STEM field Working knowledge of organic chemistry and cheminformatics Experience applying cheminformatics methods including chemical structure based clustering and similarity searches to inform the process of drug discovery Experience programming in a high-level general-purpose programming language such as Python and experience working in a Unix/Linux environment Experience with cheminformatics software including RDKit Experience with high performance computing Preferred Qualifications: Demonstrated success in contributing to the delivery of analytics solutions in Biopharma or large academic collaborative efforts in a life science field Familiarity with pipeline workflow software such as KNIME or Pipeline Pilot Experience working in a matrix environment with input from life scientists, tech, and data analysts Experience working with analytics and visualization software such as TIBCO Spotfire Excellent communication skills The Encoded Library Technologies (ELT) group at GSK operates at the leading edge of drug discovery where at any given point we are seeking affinity probes or starting points for medicinal chemistry for dozens of projects across the entire research portfolio. The ELT Platform includes a large collection of unique DNA-encoded libraries (DELs) and continually develops new DELs and new technologies for screening these libraries against multiple diverse protein targets of interest. This role will be a key contributor to the team that processes and analyzes ELT screening data to enable post selection chemistry decision making. The role will require demonstrated data science contributions from inception to delivery and a working knowledge of chemistry within a life science research setting. *For a review of ELT at GSK see: Arico-Muendel, C. C. From haystack to needle: finding value with DNA encoded library technology at GSK. MedChemComm 2016, DOI: 10. 1039/c6md00341a https://pubs.rsc.org/en/content/articlelanding/2016/md/c6md00341a Key Responsibilities include, but are not limited to: Accountable for scoping and building chemical structure and property analysis workflows that maximize impact for Encoded Library Technology data Prepare specialized visualizations of ELT data for team members, enabling downstream decision making for the Post-selection Chemistry group. Contribute to the exploration of new analysis methodologies as they apply to Encoded Library Technology and/or small molecule discovery associated data Contribute to documentation and training materials as part of full lifecycle management to ensure embedding in the scientific organization Improve current hit identification processing scripts Basic Qualifications: BS in STEM field Working knowledge of organic chemistry and cheminformatics Experience applying cheminformatics methods including chemical structure based clustering and similarity searches to inform the process of drug discovery Experience programming in a high-level general-purpose programming language such as Python and experience working in a Unix/Linux environment Experience with cheminformatics software including RDKit Experience with high performance computing Preferred Qualifications: Demonstrated success in contributing to the delivery of analytics solutions in Biopharma or large academic collaborative efforts in a life science field Familiarity with pipeline workflow software such as KNIME or Pipeline Pilot Experience working in a matrix environment with input from life scientists, tech, and data analysts Experience working with analytics and visualization software such as TIBCO Spotfire Excellent communication skills *This is a job description to aide in the job posting, but does not include all job evaluation details. *li-gsk If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site. If you require an accommodation or other assistance to apply for a job at GSK/ViiV Healthcare, please contact your local HR department. GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.