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Assoc Research Scientist

Employer
Charles River Laboratories
Location
United, PA
Closing date
Sep 19, 2021

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Sector
Science
Organization Type
Corporate
For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.

IMPORTANT: In order to be considered for this position, a resume/CV must be uploaded and submitted during the application process. Please make sure work history and education are added correctly.

Job Summary

Charles River labs is seeking an Associate Research Scientist for our Insourcing Solutions Department located in Billerica, MA.

Assist in the development of methods related to the testing and characterization of biotherapeutics using mass spectrometry. Under minimal supervision, may be responsible for method development, client interaction, interpretation and reporting of data and regulatory compliance of assigned research projects. Performs technical laboratory activities in support of client studies or procedures at client site. Performs analysis of data for quality and completeness and determines if results are as expected. Records data in compliance with company and regulatory policies and standards to meet quality and accuracy requirements.

The following are responsibilities relate to Research Associate:
• Prepare and analyze samples by LCMS based on existing assays/protocols and in compliance with SOPs and applicable regulations.
• Record project data in accordance with SOPs and/or applicable regulations.
• Perform routine testing techniques such as the following with a high degree of reliability, efficiency and accuracy:
• Peptide Mapping LC-UV/MS (MS)
• Intact Molecular Weight Analyses LC-UV/MS
• Sample Preparation such as SDS PAGE, SPE, HPLC Peak Collection
• Glycosylation Mapping via Peptide Mapping LC-MS/MS
• N- and O- Linked Glycosylation Profiling
• De novo Amino Acid Sequencing
• Various methodologies developed for QTOF, Triple Quadrupole, and MALDI-TOF
• Use of Agilent and Thermo MS Platforms

Job Qualifications

The following are minimum qualifications related to the Associate Research Scientist position:
• Education: Bachelor's degree (B.S./B.A.) or equivalent in a scientific related discipline. Related Master's degree (M.S./M.A.) or PhD/DVM preferred.
• Experience: Five years of previous laboratory experience, preferably in a pharmaceutical or contract laboratory environment
• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
• Certification/Licensure: None
• Other: Demonstrated analytical and problem solving capabilities. Understanding of regulatory requirements of study types assigned, as well as Testing Facility SOPs and the Good Laboratory Practices (GLPs). Strong organization and prioritization skills are required. An attention to detail and accuracy is a must. Effective verbal and written communication skills are required. Ability to work on problems of moderate scope where analysis of situation or data requires a review of identifiable factors. Exercises judgment within defined procedures and practices to determine appropriate action. Effective written and verbal communication skills with the ability to handle multiple projects, prioritize work and meet deadlines. Capable of data interpretation of basic characterization and analysis of biotherapeutics (glycoproteins and peptides) using mass spectrometry. Capable of anticipating and recognizing potential problems. Must be able to follow written and verbal instructions and possess good interpersonal skills that are conducive to effective communication.

IMPORTANT: A resume is required to be considered for this position. If you have not uploaded your resume in your candidate profile, please return to upload field and attach your resume/CV.

About Insourcing Solutions
Charles River Insourcing Solutions℠ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutions℠ provides you with the ability to maintain control of your facility and expertise while leveraging available space.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.

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