For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
We are seeking a Associate Scientist for or our Immunology Team site located in Mattawan, MI.
The following are responsibilities related to the Associate Scientist:
This Associate Scientist is responsible for developing and validating methods to quantify chemical entities according to applicable Standard Operating Procedures (SOPs) and/or GxP regulations. The individual in this role is proficient in the use of instrumentation and laboratory techniques and executes method development and validation. An Associate Scientist is expected to work independently, participate in process improvement initiatives, and may function as a Principal Investigator or Study Director.
The following are minimum qualifications related to the Associate Scientist position:
* PhD in relevant field and 0-2 years of relevant experience; or
* MS/BS/BA in relevant field and 5-7 years of relevant experience; or
* HS/GED/Associates and 10+ years of relevant experience.
* Proficient using laboratory software applications (i.e., LIMS and data acquisition software).
* Working knowledge of GxPs and industry guidance documents.
* Positively contributes to quality metrics by maintaining minimal level of laboratory errors and failed runs.
* Ability to work extended hours beyond normal work schedule to include, but not limited to, evenings, weekends, extended shifts and/or extra shifts, sometimes on short notice.
* Familiarity with Microsoft Office Suite.
* Ability to work under specific time constraints.
* Develops and performs quantitative and semi-quantitative ligand binding and/or cell-based assays in biological matrices to support pre-clinical and clinical studies during the large molecule drug development process.
* Performs a variety of lab techniques including buffer and solution preparation, sample processing, tissue lysis, cell culture, and proper handling of critical assay reagents.
* Collection of data is accurate and contemporaneous while maintaining timelines.
* Knowledge of FDA guidance, GLP requirements, industry standards, and company SOPs.
* Design and perform experiments, analyze data and communicate results and conclusions.
* Authors assay methods.
* Leads or assists in troubleshooting of methods that are not performing properly Provides support, training, and mentorship to others.
* Collaborates across multiple departments in order to adhere to timelines and produce quality data.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.