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Research Scientist I - Molecular Enzyme Division

Employer
New England Biolabs, Inc.
Location
Ipswich, MA
Closing date
Oct 18, 2021

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Sector
Science
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The Molecular Enzymology Division of New England Biolabs (NEB) is inviting applications for a Research Scientist I who will be involved in the discovery and biochemical characterization of enzymes involved in nucleic acid modification. The successful applicant will employ computational, genomic, and enzymology tools for enzyme screening and functional assessment. Research will be undertaken in a highly collaborative and intellectually open environment where oral communication of ideas and publication of results are expected.

Primary Responsibilities:

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Apply structure-mechanism driven approaches for enzyme discovery.

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Express, purify, and biochemically characterize enzymes with novel chemistries.

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Apply high throughput analytical methods for functional characterization.

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Perform binding and kinetic studies using absorbance and fluorescence-based stopped-flow dependent methods.

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Collaborate with investigators internally and externally.

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Communicate findings to the scientific community through publications and presentations.

Required Qualifications and Experience:

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Ph.D. in protein biochemistry, molecular biology, or related field.

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A strong foundation in functional assay design.

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A strong grasp of bioinformatic tools for enzyme pathway optimization, protein sequence and structure homology, enzyme family identification.

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A strong foundation in chemistry.

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Protein expression and purification skills.

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Enzyme kinetics knowledge such as steady-state and transient-state kinetics.

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Strong analytical skills.

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Strong desire to learn new skills and to expand the scopes of the research through internal and external collaborative efforts.

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Strong record of scientific publication.

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Strong interpersonal skills and excellent verbal and written communication skills.

Preferred Qualifications and Experience:

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Familiarity with analytical chemistry techniques such as HPLC and MS.

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Knowledge of computational tools for enzyme pathway reconstruction.

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Desire to mentor student interns.

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Personal drive to lead several projects in a technically challenging field.

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Willingness to learn and master new techniques

EEO Statement

New England Biolabs is committed to fostering a diverse and inclusive community; as an EEO/AA employer, New England Biolabs considers applicants for employment without regard to, and does not discriminate on the basis of, race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability. More in-depth details of EEO are available here.

Information regarding New England Biolabs commitment to Diversity, Equity and Inclusion can be found here.

New England Biolabs is a participating employer in the Employment Verification ( E-Verify ) program.

OFCCP's pay transparency policy can be found on OFCCP's website at www.dol.gov/ofccp

If you need an accommodation for any part of the employment process because of a medical condition or disability, please send an email to hr@neb.com or call 978-927-5054 to let us know the nature of your request.
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