Sr Research Associate I, Upstream Process Development - 8,000 Sign On
United States - California - Oceanside
Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.
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Sr Research Associate I - Early/Late Stage Upstream Process Development
Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. Together we deliver life-saving therapies to patients in need. With the commitment and drive you bring to the workplace every day, you will be part of a team that is changing the world and helping millions of people live healthier, more fulfilling lives. Our worldwide staff is a close community where you can see the tangible results of your contributions, where every individual matters, and everyone has a chance to enhance their skills through ongoing development. Our scientific focus has resulted in marketed products that are benefiting hundreds of thousands of people, a pipeline of late-stage drug candidates, and unmatched patient access programs to ensure medications are available to those who could otherwise not afford them. By joining Gilead, you will further our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases.
Gilead Sciences is currently seeking a Sr. Research Associate I in our Upstream Process Development group at our Oceanside facility in Southern California. We are seeking a highly motivated, team-oriented individual to execute experiments to support cell culture process development at both early and late stages for recombinant protein and novel platform programs. General activities will include shake flask and bioreactor experiments, process development and automation, and manufacturing and technology transfer support.
Specific Skills and Responsibilities for Position:
Previous hands-on experience with mammalian cell culture
Basic understanding of process scale-up and GMP manufacturing
Strong organizational and planning skills, as well as an aptitude for creative problem solving
Experience in statistical analyses and data visualization using tools such as JMP and Spotfire
Basic understanding of programming languages and techniques (eg. Matlab, Visual Basic)
Support upstream bioprocess development activities including clone selection, technology development, media development, process optimization, and process characterization studies
Conduct hands-on laboratory cell culture operations at shake flask, bench-top, and pilot scales
Collaborate with technical operations and biologics production teams to transfer process to and support pilot scale and clinical manufacturing upstream operations
Participate in collaborative effort to improve upstream data collection, data management, and data visualization methodology
Apply excellent technical writing, presentation, and other communication skills to solve complex problems
Collaborate in cross-functional groups to technical reports and presentations to achieve common business goals
Essential Duties and Job Functions:
Plans and executes assigned experiments that support process development activities and project goals
Selects appropriate methods and techniques in performing experiments
Recommends alternatives, researches new methods and techniques and proactively seeks out senior personnel to discuss potential solutions to problems
Contributes to early and late stage upstream process development experimental efforts as required
Contributes to research programs and platform improvement utilizing statistical Design of Experiments (DoE)
Participates in group meetings. Presents results of work, interprets data, and draws conclusions regarding presented material and nature of work
Demonstrates good verbal communication and interpersonal skills to provide insight into the processes used to achieve results of assigned tasks
Contributes to team's effort to improve data collection, management, and visualization standards using basic computer programming techniques and modern visualization software
Participates in improvement of upstream process control systems, including automation efforts
Demonstrates ability to recognize anomalous and inconsistent results and interpret experimental outcomes
Always works with safety in mind
Required Knowledge, Experience and Skills:
2+ years of experience with BS degree in a relevant scientific discipline.
0+ years of experience with MS degree in a relevant scientific discipline.
Preferred Training and Experience:
Chemical/Biochemical Engineering, Biochemistry, Biology, Bioengineering, or a related discipline of study
Must be able to work effectively in cross-functional teams
Previous work experience in a GMP-facility
Basic familiarity with Matlab or another programming language
Basic familiarity with industrial control systems and visualization tools, such as DeltaV and PI
* This Position qualifies for a $8,000 Sign-on Bonus, $4,000 payable within 30 days of start date and $4,000 payable following 6 months of continuous employment. Payments are subject to a 1-year repayment agreement from date of payment issue.
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