For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, well help you build a career that you can feel passionate about.
We are seeking a Senior Scientific Associate (In Vitro Toxicology) for our Safety Assessment group site located in Cleveland, Ohio.
Provide scientific support for nonclinical research or laboratory-based studies; perform basic to complex study management tasks and interpretation and reporting of study data/conclusions. Support development and execution of biochemical and cell-based assays, as well as novel alternative methods for in vitro toxicology assessment.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
Oversee study start-up procedures requiring cross-departmental interaction with all key study personnel.
Participate in and coordinate all phases of the study planning process with appropriate departments.
Generate high-quality protocols, amendments, and reports appropriate for assigned studies.
Function as contact for the planning and execution of sponsor interaction related to assigned studies.
Review, interpret, integrate, and present data on assigned studies, using the assistance of senior scientific staff as appropriate.
Function as contact for the planning and execution of sponsor interaction related to assigned studies, including proposal management and study scheduling, conduct and reporting.
Assist in generating study protocols and laboratory-based procedures, including those for various regulatory guidelines, and obtain sponsor approval.
Assist in assuring that all data for the studies are accurately recorded and verified.
Use of automation and relevant computer programs to analyze and interpret screening results.
May function as a study director or project scientist on assigned studies of basic complexity and participate in method development and validation activities.
May serve as an interim or alternate (secondary) scientific contact in the event an assigned study director or project scientist is unavailable.
Ensure project is in compliance with Good Laboratory Practice (GLP) regulations as they apply to the conduct of nonclinical research as required.
Contribute to department operations improvement in areas such as process development, Standard Operating Procedure (SOP) revisions, department inspections, and equipment maintenance.
Perform all other related duties as assigned.
Education: Bachelor's degree (B.S./B.A.) or equivalent in a scientific related discipline. Masters degree in Cell Biology, Biochemistry, or Toxicology strongly preferred.
Experience: Minimum of 2 to 5 years related experience in a contract research organization (CRO), academic, biotechnology or pharmaceutical environment. Previous experience developing and interpreting the results of complex in vitro toxicology assays and/or experience working to GLP standards highly preferred.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Other: Effective written and verbal communication skills. Ability to handle multiple projects, prioritize work and meet deadlines. Proficiency in the use of standard software including Microsoft Excel, Word, PowerPoint, etc. and with standard laboratory calculations.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.
At Charles River, we are passionate about our role in improving the quality of peoples lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.
Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet