Scientist II, Physicochemical Characterization (req2019)

Frederick National Laboratory
Frederick County, MD
Closing date
Oct 20, 2021

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The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.


* Assist in the physicochemical characterization and development of new analytical methods for evaluating nanomedicines
* Perform daily operation of AF4/SEC-MALS, RP-HPLC, LC/MS, and GC/MS instruments
* Serve as a technical authority and mentor in the absence of the lead laboratory scientist
* Be responsible for formal reporting of data including presentations and/or publications
* Stay abreast of current research techniques and remain knowledgeable in pertinent areas through reading literature and by attending scientific presentations


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below

* Possession of a PhD degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) in Analytical Chemistry, Physical Chemistry, Organic Chemistry, Chemical Engineering or related discipline or eight (8) years of related experience. Foreign degrees must be evaluated for U.S. equivalency
* In addition to the education requirement, a minimum of two (2) years of related experience
* Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:

* Three (3) years relevant experience
* Experience with physicochemical characterization of nanoparticles using methods such as AF4/SEC, RP-HPLC, and LC/MS
* Formulation experience of nanotechnology-based drug delivery platforms
* Ability to perform complex assignments independently as well as work effectively as part of an interdisciplinary team
* Proven track records that include conference presentations and peer-reviewed publications


* This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

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