Ph.D. Position in Cancer Immunology
- Employer
- University of Basel
- Location
- Basel, Switzerland
- Closing date
- Dec 15, 2021
View more
- Sector
- Pharmaceutical, Business Development
- Hours
- Full Time
- Organization Type
- University and College
- Jobseeker Type
- Academic (e.g. 'Lecturer')
You need to sign in or create an account to save a job.
Applications are invited for a Ph.D. Position in Cancer Immunology at the Department of Biomedicine, University Hospital Basel and University of Basel. The position is set to start from 1st February 2022 or upon agreement. Salaries are according to the current SNSF rates.
Your position
The successful candidate will work on molecular and cellular mechanisms underlying cancer-associated T cell exhaustion. The overall goal of this work is to delineate the metabolic heterogeneity of CD8 T cells in human tumors and characterize key metabolic pathways underlining the development of exhausted T cells. This knowledge will help to develop and implement novel strategies for cancer immunotherapy. Experimental systems include patient-derived tumor infiltrating lymphocytes (TILs), T cell cultures and murine tumor models.
Selected publications of our lab and our close collaborations include:
Voabil et al, Nat Med 2021; Trueb M et al, JITC 2020; Yu YR et al, Nat. Immunol 2020; Wang et al, Nat. Immunol 2020; Claus et al, Science Transl Med 2019; Trefny et al, Clin Cancer Res 2019; Cheng, Nat. Immunol 2019; Stanczak, J Clin Invest 2018; Thommen, Nat Med 2018
Your profile
We offer you
Your position
The successful candidate will work on molecular and cellular mechanisms underlying cancer-associated T cell exhaustion. The overall goal of this work is to delineate the metabolic heterogeneity of CD8 T cells in human tumors and characterize key metabolic pathways underlining the development of exhausted T cells. This knowledge will help to develop and implement novel strategies for cancer immunotherapy. Experimental systems include patient-derived tumor infiltrating lymphocytes (TILs), T cell cultures and murine tumor models.
Selected publications of our lab and our close collaborations include:
Voabil et al, Nat Med 2021; Trueb M et al, JITC 2020; Yu YR et al, Nat. Immunol 2020; Wang et al, Nat. Immunol 2020; Claus et al, Science Transl Med 2019; Trefny et al, Clin Cancer Res 2019; Cheng, Nat. Immunol 2019; Stanczak, J Clin Invest 2018; Thommen, Nat Med 2018
Your profile
- High interest in molecular and cellular mechanisms of T cell exhaustion
- Master in life sciences/biology or related fields
- Experience in cellular immunology, preferentially human tumor immunology, including multidimensional flow cytometry, is desirable
- Experience with metabolic assays is advantageous
- Knowledge of bioinformatics and high-throughput data analysis is advantageous
- Curious, well-organized, highly motivated and independent
- Team player and aptitude to work in an international research group and department
- Fluent in English (speaking and writing)
We offer you
- Affiliation with the Department of Biomedicine structured Ph.D. program
- A stimulating, challenging, and interdisciplinary translational research project
- A very active scientific environment in translational cancer immunology & immunotherapy
- National and international network with numerous academic research projects and industrial collaborations
- State-of-the-art facilities and direct access to translational research
- Opportunities to develop a structured academic career
You need to sign in or create an account to save a job.
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert