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Scientist I

Employer
Eurofins Lancaster Laboratories
Location
Saint Charles County, MO
Closing date
Dec 3, 2021

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Sector
Science
Organization Type
Corporate
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Job DescriptionEssential Duties and Responsibilities:
  • Performs work in a laboratory setting, meeting the physical job requirements of a lab role.
  • Conducts production assays primarily in ADME Toxicology Services, but may support BioMAP®, Immunosignaling, Ion Channel, and/or OncoPanel™ Services based on business needs;
  • Develops Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK applications
  • Develops analytical methods supporting project teams both internally and externally for new assay development.
  • Performs Troubleshooting and Maintenance of Mass Spectrometers and HPLC units. Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
  • Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
  • Provides solutions to more complex problems, identifies and initiates process improvements
  • Maintains high data quality and reproducibility.
  • Performs data and report QC review within the department, and may support study director.
  • Takes ownership of client projects with minimal supervision.
  • Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems.
  • Understands and complies with requirements for work performed at a GxP site.
  • Completes required training and supports 100% of Employee Health and Safety requirements.
  • Demonstrates proficiency with, care and maintenance of lab equipment and department assets.
  • Conducts responsible use of confidential IT and business systems, as required.
  • Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting.
  • Supports unit goals and demonstrates Eurofins' competencies, as defined in the job plan.
  • Provides training to colleagues and external end users, when required.
  • Contributes to scientific community, and site research and development objectives.
  • Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives
  • Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines.
  • Routinely communicates project updates to internal and external clients.
  • Performs other duties, as assigned
QualificationsBasic Minimum Qualifications (BMQ):
  • Direct experience with Liquid Chromatography- Mass Spectrometry and/or ultraviolet spectrometry (LC-MS or LC-UV) in a contract research organization or industry laboratory for ADME/ DMPK applications
  • Demonstrated proficiency in High-Throughput analytical method development for small molecules
  • Direct experience with High Resolution Mass Spectrometry for large molecule analysis for ADME/DMPK/Biotherapeutics applications
  • Demonstrated technical knowledge of Metabolomics in regards to pharmaceutical drug metabolism
  • Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
  • Good communication and interpersonal skills
  • Experience working in a Quality Management System
Education/Experience (BMQ)
  • B.S. with 10 years relevant experience
  • M.S. with 7 years relevant experience
  • Ph.D. with 3 years relevant experience ? Or an equivalent of education and experience
Ability And/or Skills (BMQ)
  • Ability to read, write, and interpret documents, such as standard operating procedures and technical reports
  • Ability to perform mathematical calculations, statistical analyses, and data interpretation
  • Ability to multitask with organization and manage time effectively
  • Ability to solve practical problems and troubleshooting skills
  • Ability to work in a laboratory setting, according to physical requirements of a laboratory role
  • Lab equipment and office computer/software proficiency
  • Above average oral and written communication skills
  • Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health
  • Ability to develop new methods, and lead research and development projects
  • Ability to review and QC release data/reports
  • Ability to lead small, informal sub-teams, train, and train new team members
  • Ability to conduct mid-size projects with minimal supervision
  • Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems
  • Ability to easily support cross-functional demands
Additional Preferences
  • Scientific expertise with mass spectrometry based quantification for ADME/ DMPK applications in biological matrices.
  • Experience with analytical method development, optimization and method transfer
  • Familiarity with concepts of validation of bioanalytical methods in accordance with regulatory (FDA, ICH) guidelines
  • Experience with liquid handling, automation, solid-phase extraction (SPE), HTS applications, and large-scale screening
  • Experience in small team leadership and project management
  • Experience in leading and delivering results in R&D or innovation programs
Additional
  • For all Eurofins Discovery Services Businesses in US; Successful applicants will be required to confirm vaccination status or demonstrate eligibility for medical or religious exemptions prior to commencing employment.
Additional InformationCandidates currently living within a commutable distance of St. Charles, MO are encouraged to apply.
  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays
Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.
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