Research Scientist (Hybrid) - Protein Engineer (Rosetta) & Protein Biochemist

Gilead Sciences, Inc.
Belmont, CA
Closing date
Dec 3, 2021

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Science, Physical Sciences and Engineering, Chemistry, Biochemistry
Research Scientist (Hybrid) - Protein Engineer (Rosetta) & Protein Biochemist
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

The Biologic Discovery Team in Protein Therapeutics is seeking a highly motivated Research Scientist to join our state-of-the-art research facility at Gilead Sciences in Foster City, CA. The Biologic Discovery Team is responsible for the design and selection of large therapeutic drug candidates, with many of the molecules of interest being novel and complex biologics.

The successful candidate will have expertise in computational protein design, preferably Rosetta, and wet lab experience in the molecular biology and/or biochemistry. Furthermore, the scientist will be a part of a broad multidisciplinary team with capabilities in protein engineering, cloning, expression, purification and characterization of large molecule drug candidates.


Drive protein design/engineering as well the proof-of-concept of novel biologics molecules.

Act as a scientific leader with the ability to drive innovation, lead projects and teams, solve complex technical problems and work independently and in cross-functional teams.

Develop and implement innovative technologies to improve efficiency and speed in the Biologics organization.

Provide scientific results that support the generation of publications, patents, or regulatory submissions, and participate in internal and external scientific meetings.

Basic Qualifications:

Doctorate degree


Master's degree and 6 years of scientific experience


Bachelor's degree and 8 years of scientific experience


A strong track record of research accomplishments in protein design and protein engineering.

Familiar with one or more structural modeling programs such as Rosetta, MOE, Schrodinger, etc.

Experience in laboratory techniques supporting structural biology and molecular biology.

Understanding of protein biophysical and biochemical properties that relate to molecule stability.

Strong communication and interpersonal skills, and the ability to work flexibly in a dynamic and collaborative environment.

Demonstrated a strong track record of independent critical thinking and scientific achievement in research, exemplified by publications in highly regarded journals, conference presentations or generation of intellectual property.

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S. employees and contractors to receive the COVID-19 vaccines as a condition of employment. "Full vaccination" is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster.



Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

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