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The Division of Biology and Biological Engineering (BBE) at Caltech is seeking a Director for our Stem Cell and Embryo Engineering Center (SEEC). The SEEC is a Resource Center offering state-of-the-art stem cell and embryo manipulation techniques to enable research of faculty across the BBE Division. Job Duties
Stem Cell and Embryo Engineering
- The successful candidate will carry out state-of-the-art techniques for the field of mouse and human stem cell and embryo research, including stem cell derivation, culture, genome editing, electroporation, cryopreservation of gametes, cloning, chimeras, embryo transfer to foster mothers, microinjections and live-cell imagining.
- The Director will use his/her personal skills in stem cell and embryo manipulations to enable the above procedures. He/She will interact with faculty members to devise appropriate experimental strategies.
- In addition to mice, the Director will develop experimental stem cell and embryo approaches applicable to other mammalian species.
Management and Leadership
- The Director will train and supervise staff members working in the Resource Center toward the common goal of ensuring the Center is at the forefront of new developments. They will contribute to making decisions on hiring, promotions, salary changes, performance evaluations, and terminations.
Animal Care and Well-Being
- The Director will plan and oversee day-to-day operations and administration of the Resource Center. Part of his/her time will be spent in Caltech's animal facilities ensuring that all Resource Center operating procedures meet the requirements of the Office of Laboratory Animal Resources (OLAR) and Federal and State regulations governing the care and treatment of animals in research.
Budgeting and Administration
- Coordinating with Division Administration, the Director will manage and administer a charge-back system for services and participate in choosing and purchasing equipment in the development of new facilities.
- The Director is a staff position which reports to a responsible faculty member and to a faculty steering committee that provides oversight of the Center.
- Ph.D. Degree in stem cell and/or developmental biology.
- Experience and knowledge of methods for stem cell culture and derivation and genetic manipulation, oocyte and embryo culture and manipulation, electroporation, embryo transfer into foster mothers, cloning, and molecular biology for CRISPR mutagenesis.
- Experience in management at either research project or facility level.
- Ability to develop and maintain housekeeping and safety protocols and to establish procedures for maintaining pathogen-free rodents.
- Understanding of Federal and State laws, regulations, guidelines, and standards for the treatment of laboratory animals.
- Strong interpersonal and communication skills and the ability to effectively collaborate with research groups inside and external to Caltech.
- Ability to supervise and train assigned staff including organizing and scheduling work assignments.
- Budget planning and accounting skills.
- Ph.D. in mammalian developmental biology or embryonic stem cell biology with postdoctoral experience.