Senior Scientist / Principal Scientist, Pharmacology

American College of Clinical Pharmacology
Reports To: Sr. Director, Head of Clinical Pharmacology

Location:(Cambridge, MA)

Company Overview:

METiS Pharmaceuticals Inc is a well-funded biotech start-up building our office in Cambridge, MA. We have a unique technology platform that has the potential to drive best-in class drug assets in a wide range of therapeutic areas. Through the integration of machine learning, quantum simulation, and high-throughput experimentation, we enable scientists to rapidly, comprehensively, and intelligently develop novel drug candidates. METiS is founded by an enthusiastic team of MIT researchers and serial entrepreneurs. Our cross-disciplinary expertise and deep industry experiences allow METiS to harness AI to boldly deliver revolutionary therapies for patients with serious diseases.

Top Reasons to Work with Us:

• Well-Funded
• Impactful Projects

Summary:

We are seeking a highly skilled, motivated, and collaborative preclinical pharmacology scientist to join our team. This position offers the opportunity to be involved in the critical identification, selection and characterization of drug candidates and their progression towards the clinic. This scientist will play a key role in designing in vitro and vivo pharmacology studies to demonstrate the proof-of-concept in preclinical studies for various therapeutic areas.

Key Responsibilities:

• Design and execute in vitro and in vivo studies to understand drugs' mechanism of actions and to demonstrate proof-of-concept in preclinical models
• Design and execute preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of drugs, and to translate PK/PD relationship from preclinical to clinical using modeling and simulation
• Serve as a pharmacology representative and the subject matter expert in the interdisciplinary team, contributing to the execution of experiments in support of overall research activities and project goals
• Participate in the selection and
• management of CROs/academic sites in the conduct of in vitro/in vivo studies

Job Qualification:

• PhD in Molecular Biology, Pharmacology, or a related field
• Minimum 4 years of industry experience
• Experience managing studies conducted at CROs
• Experience in PK/TK principles and design, execution, data analysis, interpretation and statistical analysis of ADME/PK and PK/PD studies
• Experience successfully preparing Pharmacology sections of regulatory documents
• Strong communication skills, presentation skills and cross-functional collaboration are required

RECRUITING & STAFFING AGENCIES:METiS Pharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to METiS or its employees is strictly prohibited unless contacted directly by METiS recruiting team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of METiS, and METiS will not owe any referral or other fees with respect thereto.

Job Information

• Job ID: 59462920
• Location:
  Cambridge, Massachusetts, United States
• Company Name: METiS Pharmaceuticals

Please refer to the company's website or job descriptions to learn more about them.

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