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Research Associate/Senior Research Associate

Employer
Arcus Biosciences, Inc.
Location
Hayward, CA
Closing date
Apr 8, 2022

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Research Associate/Senior Research Associate - DMPK

Arcus Biosciences is seeking a highly motivated and team-oriented individual for the position of Research Associate in the Drug Metabolism and Pharmacokinetics (DMPK) Department. The successful candidate will be responsible for conducting routine in-vitro ADME studies, qualitative and quantitative analysis of small molecules using LC-MS/MS, to support multiple drug discovery and development projects.

Responsibilities include, but are not limited to:
  • Perform LC-MS/MS method development and quantitative analysis of small molecules in various biological matrices.
  • Conduct routine in vitro studies including, but not limited to, metabolic stability, CYP P450 inhibition and Time Dependent Inhibition assays.
  • Perform other in vitro ADME studies such as plasma protein binding, blood-to-plasma partitioning, and CYP phenotyping as needed.
  • Perform data analysis and reporting of experimental results to project teams.
  • Maintain and troubleshoot LCMS instruments.

Qualifications
  • BS/MS degree in biochemistry, pharmaceutical science, or related scientific discipline with 1-4 years of relevant experience
  • Hands-on experience in LC/MS/MS method development and quantitative analysis of small molecule using LC/MS/MS instruments, preferably SCIEX 4000, 5500 or 6500 series
  • Experience with in vitro ADME assays is highly desirable.
  • Experience with liquid handling systems, Tecan and Bravo, is a plus.
  • Detail-oriented, strong work ethic, self-motivated, and proven ability to work both independently and collaboratively in a team environment
  • Excellent communication and writing skills


Arcus is an EEO
#LI-EW1

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