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Research Scientist Bioinformatics

Employer
Gilead Sciences, Inc.
Location
Belmont, CA
Closing date
Jan 25, 2022

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Sector
Science
Organization Type
Corporate
Research Scientist Bioinformatics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

We are seeking a highly talented and motivated Bioinformatics Scientist to join the Research Data Sciences team to support research projects from early target discovery to biomarker identification with a focus in inflammation and fibrosis. The successful candidate will have the opportunity to work in a fast-paced and highly collaborative environment and impact high-level decision making on internal pipeline. He/she will take a lead role in interpreting and integrating large-scale datasets (scRNA-seq, bulk RNA-seq, GWAS etc.) and employing rigorous bioinformatics approaches to enable research objectives. The successful candidate will have the ability to formulate scientific questions into coherent analytical efforts and communicate analysis results and scientific findings to project teams and across different research functions.

Essential Functions:
  • Develop and implement quality assessment, analysis and data visualization for multi-omics datasets (e.g., single cell/nuclei sequencing, RNA-Seq, GWAS, TCR-Seq, etc.)
  • Develop novel predictive models using computational techniques and machine learning for analysis of large -omics and high dimensional data from internal, publicly available, commercial, and real-world datasets to enable target identification/assessment, drug combinations, understanding of MOA, disease mechanisms, etc.
  • Collaborate with cross-functional teams to analyze and interpret complex large datasets and communicate findings and recommend follow-up actions in multiple settings (including: 1:1, seminars, group, and project meetings)
  • Actively identify new opportunities/questions that advanced computational methods can address and develop/evaluate solutions both independently and collaboratively
  • Develop visualization and analytical tools to enable data analysis and exploration by the broader Gilead Research community
  • Provide expertise and technical consultation for external collaborations/partnerships in academia and industry


Knowledge, Experience and Skills:
  • Hands-on experience analyzing, interpreting, and integrating large-scale, multi-omics biological datasets, such as genomics, transcriptomics, epigenetics, proteomics, high throughput screening, and/or molecular pathology, etc is required
  • Experience in analysis of single-cell RNAseq data is required, and expertise in multi-omics data analysis within inflammation and immunology areas is preferred
  • In-depth knowledge of bioinformatics algorithms, genomic and proteomic technologies and high-throughput experimental techniques, e.g. next generation sequencing technologies, single cell technologies, and their applications.
  • Strong statistics knowledge, such as statistical power, univariate and/or multi-variate analysis, unsupervised and supervised analysis, regression analysis, survival analysis, and machine learning, etc.
  • Demonstrated ability to collaborate with research scientists and cross-functional teams, and to manage multiple projects in a fast-paced working environment.
  • Excellent oral/written communication skills and ability to present to senior management team.
  • Demonstrated the ability to synthesize scientific questions into a coherent research effort and communicate scientific findings across different functional teams
  • A proactive and self-motivated individual with a strong work ethic and scientific rigor, ability to work in a dynamic environment and able to manage multiple objectives in parallel and adapt to changing priorities


Required Qualifications:
  • A Ph.D. in bioinformatics, genomics, computer science or related field with strong hands-on analytical experience of single cell sequencing data. Post-doctoral fellowship or industry experience is preferred.
  • Proficient in statistical and scripting programming languages, such as R, Python, etc. is required
  • Extensive experience with multi-omics data and large-scale biological datasets is required
  • Strong publication record, especially in high-impact peer-reviewed journals
  • Strong scientific background and in-depth understanding of genomic and proteomic technologies and high-throughput experimental techniques is required
  • Excellent interpersonal and communication skills that foster collaboration and teamwork


For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.


For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S. employees and contractors to receive the COVID-19 vaccines as a condition of employment. "Full vaccination" is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

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