This job has expired

Synthetic Organic Chemist, CTM Group

Cambridge Isotope Laboratories, Inc.
Tewksbury, MA
Closing date
Jan 15, 2022

View more

Science, Chemistry, Organic Chemistry
Organization Type
You need to sign in or create an account to save a job.
Cambridge Isotope Laboratories, Inc. (CIL) has an exciting opportunity to join our GMP Production team as a Synthetic Organic Chemist, CTM Group based onsite in our Tewksbury, MA location. As the leading company in a niche scientific market, CIL works with cutting edge researchers in clinical diagnostics, metabolic research, proteomics, environmental testing, protein discovery, drug development, metabolomics, and industrial research. CIL's growing customer base spans academia, pharmaceutical and industry, enabling collaborations with Nobel laureates, industry-leading scientists, and chemists. CIL partners with leading instrument manufacturers as well pioneering research groups that have expertise in product development and drive market growth. CIL is a subsidiary of the Otsuka Pharmaceutical Group and has had consistent growth for 40 years.

The Synthetic Organic Chemist will take part in the production of chemicals for clinical trials, research chemicals as well as support the production of cGMP products in a laboratory setting under GMP guidelines. In addition to synthesis, writing, and reviewing documents, protocols, procedures, and SOPs as dictated by GMP guidelines is also an integral component of this position.


* Applying standard organic chemistry methods in the synthesis of isotopically labeled products including manufacturing under cGMP guidelines

* Applying standard organic chemistry methods in the development and optimization of synthesis routes

* Troubleshoot and optimize chemical processes as needed

* Support the Tech-Transfer from the development stage to the GMP manufacturing stage

* Take part in writing of documents pertaining to the GMP production as needed

* Maintain a supply of lab equipment, instrumentation, and reagents

* Responsible for coordinating and planning of manufacturing activities with production manager

* Other duties as required


* Bachelors or Masters degree in Chemistry with a minimum of 2 years experience in a similar manufacturing environment

* Strong verbal and written communication skills

* Excellent communication, documentation and teamwork skills required

* Experience with analytical techniques such as NMR, HPLC and GC is a plus


CIL offers a competitive salary and a comprehensive benefit program including generous paid time off, health insurance with 100% company paid deductibles, Long Term Incentives and 6% matching 401K plan.

CIL is an EEO/Affirmative Action employer.

Learn more about us on our website: [

About us:

Cambridge Isotope Laboratories, Inc. (CIL) is the worlds leading producer of stable isotopes [ stable isotope-labeled compounds. With nearly 600 employees and laboratories in four countries, CIL specializes in the process of labeling biochemical and organic compounds with highly enriched, stable (nonradioactive) isotopes of carbon, hydrogen, nitrogen and oxygen. Our chemists substitute common atoms (e.g., 1H, 12C, 14N, 16O) with rare, highly valued isotopes (e.g., 2H or D, 13C, 15N, 18O) so that the final product can be readily measured or traced using mass spectrometry (MS) or nuclear magnetic resonance (NMR). CILs products are utilized in laboratories, medical, government and academic research centers and health care facilities worldwide.

We are proud that CIL products have contributed to medical advancements in cancer research, new-drug development, environmental analysis, and medical diagnostic research. In the past decade, as the fields of proteomics and metabolomics have developed as leading techniques for determining biomarkers for disease presence, progression and the monitoring of therapeutic response, CIL has worked closely with industry leaders and researchers to provide the stable isotope-labeled tools needed for improved quantitation and qualification of complex biological systems.

After decades of research, stable isotopes have found their place in an ever expanding commercial scale applications in pharmaceuticals, semiconductors, flat panel displays as well as other high technology fields specifically with deuterium oxide (D2O) and deuterium gases. Pharmaceutical companies have begun to investigate deuteration of molecules that may provide advantages over their existing nondeuterated counterparts. In addition, increasing research into the potential medical advantages of new deuterated drugs is also occurring. In high technology, deuterated organic molecules and deuterium gas are commonly used in the manufacturing of microelectronics and OLEDs, which contribute to the increased lifetime of the devices.

Learn more about us on our website: [
You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert