Scientist I

Scientist I

Job Details

Job ID:
24632

Location:
450 Brookline Ave, Boston, MA 02215

Category:
Research Technician/Scientist

Employment Type:
Full time

Work Location:
Onsite:Up to 1 day remote/wk

Overview

The Center for Immuno-Oncology (CIO) of the Dana-Farber Cancer Institute is seeking applications for a research scientist within the Tissue Biomarker Laboratory. The laboratory is dedicated to the development and implementation of novel analytical methods applicable for the study of tumor immunity using human biopsy samples. Techniques in routine use include multiplex immunofluorescence coupled with digital image analysis, targeted gene expression profiling, and customized fluorescence in situ hybridization assays that are applied to fixed biopsy samples from patients receiving immune checkpoint blockade, CAR-T cells, and novel immune therapies. The laboratory has also been validating multiplex ion beam imaging (MIBI) coupled with computational image analysis as the next-generation tool for highly multiplexed tissue imaging.

The Tissue Biomarker Laboratory serves the clinical/translational needs of DFCI investigators, is a member of the NIH-sponsored Human Tumor Atlas Network, and an NIH-sponsored Cancer Immune Monitoring and Analysis Center. Over the past 5 years, the laboratory has contributed to over 50 publications (http://(see application details) It is anticipated that the breadth and scope of the laboratory will grow along with advances in tissue analysis and immunotherapies to maintain the goal of gaining a deep and thorough knowledge of human tumor immunology.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Requirements

Responsibilities will include initiating and managing research projects, overseeing data collection and analysis, and working with the Lead Scientist and Laboratory Director to prepare manuscripts and research proposals. Research projects will largely be collaborative studies involving extensive interactions with members of an adjacent histopathology laboratory, technicians, biomedical researchers, pathologists, clinicians, bioinformaticians, and data scientists. Experience working with teams and managing technicians is preferred.

Qualifications

A qualified candidate should have a Ph.D. in a biomedical-related discipline, preferably immunology, biomedical engineering, and/or cancer biology, and experience in computational data analysis or quantitative microscopy. New PhD grads, post-docs and/or staff scientists are encouraged to apply!

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.