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Analytical Development Research Associate

Durham County, NC
Closing date
Jan 18, 2022

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Science, Pharmaceutical, Laboratory, Clinical Research Associate
Organization Type
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Job Description
About Us

Shattuck Labs, Inc. (NASDAQ: STTK) is a clinical-stage biotechnology company pioneering the development of bi-functional fusion proteins as a new class of biologic medicine for the treatment of patients with cancer and autoimmune disease, with three ongoing Phase 1 clinical trials. Compounds derived from Shattuck's proprietary Agonist Redirected Checkpoint, ARC®, platform simultaneously inhibit checkpoint molecules and activate costimulatory molecules within a single therapeutic. The company's SL-172154 (SIRPα-Fc-CD40L) program, which is designed to block the CD47/SIRPα checkpoint interaction and simultaneously agonize the CD40 pathway, is being evaluated in two Phase 1 trials. A second product candidate, SL-279252 (PD1-Fc-OX40L), is being evaluated in a Phase 1 trial in solid tumors or lymphomas. Additionally, the company is advancing a proprietary Gamma Delta T Cell Engager, GADLEN™, platform, which is designed to bridge gamma delta T cells to tumor antigens for the treatment of patients with cancer. Shattuck has offices in both Austin, Texas and Durham, North Carolina. For more information, please visit:

About the Position

As a Research Associate in Analytical Development, you will be a member of a growing team with talented scientists. This team is responsible for analytical method development and product characterization in support of process development for the clinical manufacturing of ARC and GADLEN programs. Responsibilities will include sample analysis, data analysis, authoring technical reports, supporting technology transfer into Q.C., and generate documents for internal and external analytical support for manufacturing. Routine interactions with the cell line development, upstream process development, downstream process development, and research groups at Shattuck is a must. The ideal candidate is also versed in GxP lab practices.

The Research Associate in Analytical Development will be actively involved in working with the Technology operations leadership to develop strategic planning for development of platform methods for the ARC and GADLEN programs.

Required Qualifications

We are looking for professionals with these required skills to achieve our goals:
  • B.S./M.S. in in Chemical/Biochemical Engineering or related Biological Sciences with >1 years of experience in the Pharmaceutical/Biotech industry in a process development setting for biopharmaceuticals
  • Experience in use of analytical instrumentation (plate readers, HPLCs, capillary instruments)
  • Experience in analytical assays (CGE, SDS-PAGE, HPLC, UPLC, Octet, etc.)
  • Demonstrated ability to work collaboratively in a lab environment

If you have the following characteristics, it would be a plus:
  • Knowledge of ICH/USP guidelines
  • Knowledge of Analytical Method Development, Qualification, and Validation
  • Excellent written and communication skills
  • Experience in data analysis
  • Experience in authoring technical reports
  • Strong desire to work at the bench
  • Working knowledge of cGMP manufacturing processes for biopharmaceuticals
  • Knowledge of process development phases

Note to External Recruiters: Our Human Resources department manages all open positions and candidate recruitment. We ask that recruiters not contact employees or hiring managers directly to present candidates or solicit business. We will consider failure to comply with this request when determining whether to enter a professional relationship with a recruiting agency. The submission of unsolicited resumes does not create any obligations for Shattuck Labs, implied or otherwise.

Note to Job Applicants: New employees will be required to be in compliance with Shattuck's EEOC-compliant COVID-19 vaccination policy.
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