Cell Line Engineer

About VitroLabs:

VitroLabs is a venture-backed biotechnology startup working towards a world where science is used responsibly to provide positive impact for business, the planet, and all living things. By harnessing novel applications of science and technology, we've developed a process to grow real leather that is cruelty-free and better for the environment.

About the role:

Reporting to the Cell Biology Lead, the Cell Line Engineer will use receptor engineering and extracellular matrix production regulation to develop novel mammalian cell lines that will help facilitate more efficient and cost-effective tissue formation. The Cell Line Engineer works with various teams, including R&D, Product, and Operations, to support advancements in bioprocessing, scaffolding, and large-scale tissue formation.

About You:

You are an experienced cell biologist who enjoys collaborating across disciplines in order to solve complex problems. You effectively share ideas, data, and bottle-necks to technical and non-technical audiences alike. You have knowledge or interest in cellular agriculture and are excited to bring your experience in cell line engineering to this nascent industry. You are excited to join a startup team!

Responsibilities:

• Develop new cell lines by modifying growth factor signaling and extracellular matrix production mechanisms
• Develop assays to screen, isolate, and validate cell lines
• Collaborate with bioprocessing, biomaterial, and tissue bioreactor teams to transfer and develop downstream processes for the new cell lines
• Identify, suggest, purchase and operate specific equipment through established processes to support this role
• Mentor junior members with technical skills, presentations, and experimental design

Qualifications & Skills:

• Experienced in adherent and suspension mammalian cell culture
• Experience with molecular cloning and transfection including designing DNA constructs, producing plasmids, and delivering to cells using transfection or electroporation
• Genetic engineering: can use viral (lentivirus, AAV, etc.) or non viral methods (CRISPR, transposons, TALEN, ZFNs, etc.) to modify cells. Able to apply a variety of tools to validate the modification
• Cell line development: able to screen, isolate, and validate targeted cell populations
• Receptor engineering: able to design novel chimeric receptors to regulate a variety of signaling pathways
• Extracellular matrix pathway engineering: knowledge of extracellular matrix biology with an ability to develop methods to manipulate the production of extracellular matrix by the cells

Compensation:

• $110,000-120,000 annually

We offer great benefits (health, vision, and dental insurance) and challenging, impactful work. Join our growing team, work with smart and dedicated people, and help develop cutting-edge technologies that will positively impact the world.

DISCLAIMER:

The above statements are intended to describe the general nature and level of work being performed by incumbents assigned to this job. This is not intended to be an exhaustive list of all the functions, responsibilities, duties and skills required for the position, and VitroLabs Inc retains the discretion to modify functions, responsibilities, duties and skills at any time, including modifying the time devoted to such activities, deleting activities and assigning other activities.

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

VitroLabs Inc is an equal opportunity employer committed to providing employment opportunities without regard to race, color, sex (including gender identity, sexual orientation, and pregnancy), age, national origin, religion, veteran status, disability, genetic information, or any other protected status in accordance with applicable law.