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Senior Scientist

Collegeville, Pennsylvania
Closing date
Jan 21, 2022

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Science, Pharmaceutical
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Site Name: USA - Pennsylvania - Upper Providence Posted Date: Jan 13 2022 An exciting opportunity has arisen for a highly motivated molecular biologist with a passion for protein technology, to join the department of Protein, Cellular, and Structural Sciences (PCSS) at GSK's facility in Upper Providence, Pennsylvania. The primary responsibility of the department is to design, generate and validate biological reagents for discovery activities across all of GSK's therapeutic modalities. The department also provides the structural and mechanistic understanding of drug target, molecular recognition and mode of action to deliver the best molecule. In this role, the scientist will have the opportunity to work on targets supporting multiple therapeutic areas including Oncology, Immunology, Infectious Disease, Neurology and Inflammation. The successful candidate will be responsible for downstream characterization and registration of genome-edited cell reagents for use in GSK's drug discovery platforms. Key Responsibilities include, but are not limited to: Run cell characterization for cell reagent QC using molecular biology skills (PCR, sequencing, Western and Seq editing software) Maintain, QC and register a variety of cell lines Troubleshoot technical issues, keep updated with latest technologies and improve experimental procedure accordingly Work comfortably with a fast-paced and productivity-oriented laboratory environment Work in a matrix team environment to enable optimal delivery of project and department objectives to the highest possible scientific standard Independently execute laboratory experiments and/or advanced data analysis, integration and interpretation with an emphasis on providing appropriate context for data and experiments in the progress of programs and/or platforms Ensure compliance with all GSK R&D data integrity practices, ethics codes, standards and training, and safety training and practice Why you? Basic Qualifications: A Bachelor OR Master's degree in a life sciences discipline (e.g. molecular biology, cell biology, oncology) with at least 2+ years of relevant laboratory experience. Preferred Qualifications: Qualified candidates should have strong track-record in either one or more of the following disciplines: Molecular Biology, Cell Biology, Genetics If you have the following characteristics, it would be a plus: Experience with cell culture including cell lines, primary cells, co-culture models and iPSC Experience in CRISPR editing or other genome editing technologies Sequencing (Sanger and NGS), genotyping, primer/probe design, qRT-PCR, ddPCR and Snapgene/Benchling (or equivalent software) Data analysis experience, e.g. Excel or Spotfire. Ability to plan and execute multiple tasks concurrently and evaluate multiple scientific strategies in parallel where appropriate Experience demonstrating strengths in high performance behaviours, such as building relationships, flexible thinking, and enabling/driving change. Why GSK? At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader in Consumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggest changes we've made to our business in over 20 years. We're on track to separate and create two new companies in 2022: New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics science; and a new world-leading consumer healthcare company of loved and trusted brands. With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of disease together - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and as a new GSK where outstanding people thrive. Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture that is ambitious for patients - so we deliver what matters better and faster; accountable for impact - with clear ownership of goals and support to succeed; and where we do the right thing. So, if you're ready to improve the lives of billions, join us at this exciting moment in our journey. Join our challenge to get Ahead Together. *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
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