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Senior Scientist

Collegeville, Pennsylvania
Closing date
Jan 21, 2022

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Science, Pharmaceutical
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Site Name: USA - Pennsylvania - Upper Providence Posted Date: Nov 10 2021 Senior Scientist Seeking a highly motivated, flexible and experienced scientist with demonstrated expertise in reagent generation and characterization. The successful candidate will have experience in protein conjugation, purification and characterization. This individual will be responsible for purifying critical reagents (e.g. peptides, protein, antibodies and antibody fragments) with and without conjugations (e.g. biotin, ruthenium and fluorescent labels). This individual will also participate in characterization studies of purified critical reagents and generation of Certificates of Analyses for large batch lots. The successful candidate will possess a working understanding of biochemical techniques including AKTA, SPR/Octet, LC/MS, Analytical SEC as well as familiarity with analytical platforms such as ELISA and ECLIA. Responsible for the development and quality of critical reagents, including characterizing external antibody's, building isotype-specific antibody reagents, purifying proteins, conducting protein conjugations (e.g. biotin, ruthenium and fluorescent labels), assessing their purity and affinity, and generating certificates of analysis (CofA) Monitor reagents life cycle and characterization in order to assist with reagent trouble shooting effort Strong technical writing experience (SOPs, Protocols and Reports) to support all projects Reduce the risk of assay failures by producing well characterized reagents As part of reagent preparation, perform analytical testing as needed Contribute to the group's growth, by evaluating new platform/technologies or developing new techniques Holds themselves accountable for delivering high quality reagents, and be fully compliant with regulatory requirements. Adhere to agreed timelines Demonstrate ability to handle multiple projects concurrently Function well in a team and possess a good balance of creative and analytical skills Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: M.S 1 year and B.S. 3 years above of relevant experience in analytical sciences, life sciences or related field. Highly motivated team player with a proactive attitude, excellent organizational skills and a demonstrated ability to interact effectively within a multi-disciplinary team Attention to detail with excellent communication and documentation skills Preferred Qualifications: If you have the following characteristics, it would be a plus: Understanding of process of anti-idotype antibody generation. Experiences of working with CRO for critical reagent generations Multiple years of experience in protein purification, AKTA and LC/MS or LBA assay. Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
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