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Post-Doctoral Fellow-Epigenetics postdoctoral Scholar

Wayne State University
Midtown, NJ
Closing date
Jan 17, 2022

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Posting Number 045995 Position Title Post-Doctoral Fellow-Epigenetics postdoctoral Scholar Number of Vacancies 2 School/College/Division/Institutes/Centers 06 - School of Medicine Primary Department H0610-Obstetrics/Gynecology Working Conditions Typical work environment may include a laboratory and/or office environment. May require working non-standard business hours including evenings and weekends. May be required to travel to scientific conferences. Wayne State University requires all students, faculty and staff to be fully vaccinated against COVID-19 with limited exceptions. Learn more at: Essential Functions (Job Duties) Postdoctoral research associate positions are available immediately to work in the Pilsner lab on three NIH-funded projects on the role of preconception environmental exposures on sperm epigenetics and early-life development that span human cohort studies and animal models. Projects comprise of multiple population-based studies including the Sperm Environmental Epigenetics and Development Study (SEEDS), which has been enrolling couples seeking in vitro fertilization (IVF) to understand the associations between preconception paternal exposures to endocrine disrupting compounds (EDCs), such as phthalates, sperm epigenetics, and embryo development. In parallel to our human studies, we are examining embryonic inheritance of sperm epigenetics after preconception environmental exposures in male mice. Lastly, we are investigating the role of the environment on sncRNA expression of extracellular vesicles from human seminal plasma. Together, these projects utilize a variety of locus-specific and next-generation techniques such as RNA-seq, RRBS, and WGBS, as well as EPIC arrays in human and mouse sperm and mouse embryos. Opportunities for postdoc-driven independent research are also possible. The title of Postdoctoral Scholar applies to those who are paid a salary by WSU. Their salary is usually charged to a grant or contract secured by their faculty mentor. This position is time-limited and typically expires after completing 6 years of research training. The title of Postdoctoral Fellow applies to scholars who receive financial support in the form of a fellowship or stipend, usually from an outside agency, either directly or distributed through WSU on behalf of the sponsor. Typically, fellows are responsible for applying for a fellowship award. Based on the year of the scholar/fellow, this distribution will change. Earlier in their career they will directly conduct research, whereas later, as they become ready to apply for other positions or transition away from postdoc status, they focus on papers, grants etc. The functions listed in the table below are suggestions and would be best categorized and assigned by the mentor/sponsor, in close collaboration with their postdoc, as they consider and complete the Individual Development plan that each postdoc at WSU is expected to complete and revise each year. Perform scientific techniques or research protocols. Assist the Principal Investigator in designing and performing protocols. Design and perform experiments. Collect and log research data. Participate in implementing research objectives, ensuring compliance with all legal, regulatory and protocol guidelines. Assist other lab members with experiments as required. May mentor research assistants and students. With the assistance of the mentor, find and write research grants with the goal of obtaining additional research grant funding. Responsibilities may also include coordinating correspondence with applicants and grantees, acknowledging receipts of proposals, and maintaining a system to track proposals. Evaluate and perform preliminary analysis of the data using graphs, charts or tables to highlight the key points of the research results collected in accordance with the research protocols as stipulated. Prepare and present presentations regarding research project results for professional, scientific and academic conferences. Summarize and organize data results for submittal to academic and scholarly, peer-reviewed journals. Write scientific manuscripts and other documents for publication. Fact-check, proofread, and edit research documents to ensure accuracy. Maintain the laboratory work areas including routine maintenance on laboratory equipment as required. Order and organize required research supplies and records. Maintain cleanliness and organization of work station. Perform other related du Unique Duties Separate human sperm cells, isolate DNA, construct genomic libraries for next generation bisfulite sequencing analyzing data utilizing computational biology and/or bioinformatics and help prepare manuscripts. Expose mice to environmental pollutants, harvest organs of interest, isolate DNA and examine changes in transcriptome and methylome using next-generation sequencing. Analyze data utilizing computational biology and or bioinformatics and help prepare manuscripts. Qualifications Education Doctorate degree Requires advanced knowledge in a field of science or learning, predominantly intellectual in character. This knowledge is acquired by a prolonged course of specialized intellectual instruction. Experience Intermediate (3 to 4 years job-related experience) Job related experience can include doctorate training. Experience performing basic research techniques, preferred. Must have distinguished themselves in research. Prior recipient of funding for research based on individual achievements. Knowledge, Skills and Abilities Ability to work independently. Ability to secure grants and funding for research. Ability to collect, analyze, summarize and interpret research findings in reports and communicate results to the field. Knowledge of and experience with current scientific integrity principles. Excellent time management and organization skills. Excellent interpersonal skills and demonstrated ability to work with others in a collaborative environment. Microsoft office software skills. Preferred Qualifications A PhD in Molecular Biology, Biochemistry, Cellular Biology, Genomics, Environmental Health Sciences or a related field and a strong publication record are required. Candidates with a strong background in epidemiology, epigenetics, male reproductive biology, next-generation sequencing, and/or computational biology/bioinformatics are preferred. The successful candidate will be expected to work independently on projects, generate and analyze data, help graduate students, and write manuscripts. To learn more about our research, please visit Testing Requirements Not Applicable Test Scheduling Job Type Full or Fractional Time Job Category Academic Administration **Duration of Posting** Fiscal Year of Job Open Date 2022 Job Open Date (When job is posted in the system) 11-10-2021 Job Close Date (or until suitable candidate is found) Until Suitable Candidate is Found Is this position reposted? No Reposting Reason: None (New Posting) **Application Information** Background Check Requirements University policy requires certain persons who are offered employment to undergo a background check, including a criminal history check, before starting to work. If you are offered employment, the University will inform you if a background check is required. Instructions for submitting your application: In addition to submitting your application via the online hiring system, interested candidates should send the following to Dr. Richard Pilsner via email at ? 1-page letter describing their research interests ? Curriculum vitae ? Contact information of three references who may be contacted Represented Position Message **Funding/Salary Information** Salary (Minimum) (Non-Academic Only) TBD Salary (Hire Max) (Non-Academic Only) Salary (Maximum) (Non-Academic Only) Hourly Rate (Non-Academic Only) Salary Range (Academic Only) Is Position Bump Ineligible? (Non-Academic, Represented positions only. Select 'No' for Academic. Select N/A if Non-represented.) **NOTE: If 'Yes' is selected, then this is a Bump Ineligible Position (BIP). The person who bids or hires into this 100% grant funded position has no bumping rights upon grant expiration or in a reduction of force. N/A Equal Opportunity/Affirmative Action Employer including Disabled/Vets

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