MANAGING DIRECTOR, TRANSGENIC ANIMAL MODEL CORE

Summary

 

University of Michigan’s Biomedical Research Core Facilities (BRCF) - housed within the Medical School Office of Research - is seeking a motivated and experienced scientist to lead the Transgenic Animal Model Core (Transgenic Core) as Managing Director.

The incoming Transgenic Core Managing Director will assume direction of a highly experienced team, which serves the needs of University of Michigan’s extensive research community. Having created thousands of mouse and rat models since its inception in 1989, the Transgenic Core is one of the oldest and most productive research cores at the University of Michigan and enjoys a long-standing international reputation of leadership and excellence. The incoming Managing Director, in partnership with the BRCF leadership team, will shape the future of the Core to ensure that it continues to produce transgenic animal models with cutting-edge technology for a diverse and growing group of research scientists and physicians.

For an overview of the Transgenic Core, please visit: https://brcf.medicine.umich.edu/cores/transgenic-animal-model/

 

Mission Statement

 

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

 

Why Work at Michigan?

 

Being part of something greater, of serving a larger mission of discovery and care — that's the heart of what drives people to work at Michigan. In some way, great or small, every person here helps to advance this world-class institution. It's adding a purpose to your profession. Work at Michigan and become a victor for the greater good.

 

Why Join Michigan Medicine?

 

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

 

Responsibilities*

 

Science & Technology Expertise

• Keeping up to date on the genome editing and transgenic technologies to identify methods that improve the range and efficiency of transgenic rodent models for the research community

• Collaborating with scientific investigators to determine the best animal model for their research program

• Advising Core users on how to design projects with genetically engineered mice and rats, and identifying the ideal technology for their application

• Working with off-campus project collaborators in the design and validation of customized genome-editing reagents, transgenes, and gene-targeting vectors

• Leading a hands-on training program in transgenic technology for Core users

• Serving as a subject matter expert in transgenic rodent models and representing the Core as a scientific ambassador to the transgenic technology research community

• Presenting the Core’s scientific achievements at local, national, and international meetings

Core Operations Management

• Developing and implementing the Core’s strategic plan and vision

• Directing and participating in the day-to-day operations of the Core

• Optimizing workflows to ensure consistent, reliable, and timely production of genetically engineered rodent models

• Initiating projects and managing expectations of Core users

• Tracking project status and recording success rates

• Supporting Core users with letters of support to granting agencies and preparations of progress reports and manuscripts

• Developing and maintaining standard operating procedures

• Keeping track of Core expenditures pertinent to supplies of animals, reagents, equipment, and repairs

• Working with BRCF leadership and Core scientific advisory committee to enhance service offerings

• Collaborating with other BRCF cores to further promote team science

Human Resource Management

• Sourcing, interviewing, and selecting staff

• Overseeing staff on-boarding and on-going staff training opportunities

• Planning and directing Core staff schedules

• Evaluating staff productivity and efficiency

• Working with the BRCF administration office to identify and provide professional development opportunities for staff

• Creating/sustaining a diverse and inclusive work environment that is effective for team building and morale

Fiscal Management

• Managing expenses, and revenues through the use of institutional core management software, as well as preparation of an annual Core report and its presentation to the BRCF leadership team

• Working with the BRCF administration office to set, monitor, and evaluate recharge rates for the Core and set annual budgets

• Interfacing with billing and reporting software as well as University of Michigan IT to enhance usability, troubleshoot issues, and ensure timely & accurate billing

 

Required Qualifications*

 

• A Ph.D. or equivalent doctoral degree in the biological sciences, preferably with a focus on genetics, molecular biology, or transgenic animal technology
• 3-5 years of postdoctoral or equivalent experience working in transgenic animal model generation with transgenic technology
• Demonstrated expertise in CRISPR technology and its applications in transgenesis 
• Demonstrated expertise in designing gene targeting projects in mice, rats, and mammalian cells
• Demonstrated expertise in configuring and implementing genotyping assays
• Demonstrated effectiveness in managing highly experienced professional staff members and championing their efforts
• Demonstrated technical expertise in adapting advanced equipment in transgenesis procedures
• Excellent communication and organizational skills with the ability to work in a diverse, customer-based fee-for-service environment

 

Desired Qualifications*

 

• Significant experience in transgenic animal model generation with CRISPR technology
• 5-10 years of experience in embryonic stem cell technology, random DNA transgenesis, and genotyping assays
• Experience in designing and implementing genotyping assays for de novo genetically engineered mice and rats
• Experience with the generation of genetically engineered mice, rodent assisted reproductive technology services (ARTS)
• Demonstrated expertise in cryopreservation and assisted reproductive technology for rodents
• Rank of appointment, including at the faculty (research) level, based on qualifications and experience

 

Additional Information

 

The Michigan Medicine Biomedical Research Core Facilities are firmly committed to advancing Inclusion, Diversity, Equity, Accessibility, and Belonging which are core values at the Office of Research.   Our community supports recruiting and cultivating a diverse workforce, as it is a reflection of our commitments to serve the diverse people of Michigan and the world.  We strive to create a work culture where every team member feels respected, valued, and safe.

 

Background Screening

 

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

How to Apply

 

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

 

Application Deadline

 

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

 

U-M EEO/AA Statement

 

The University of Michigan is an equal opportunity/affirmative action employer.

U-M COVID-19 Vaccination Policy

COVID-19 vaccinations, including boosters when eligible, are required for all University of Michigan students, faculty and staff across all campuses, including Michigan Medicine.  This includes those working remotely.   More information on this new policy is available on the Campus Blueprint website or the UM-Dearborn and UM-Flint websites.