University of Michigan’s Biomedical Research Core Facilities (BRCF) - housed within the Medical School Office of Research - is seeking a motivated and experienced scientist to lead the Transgenic Animal Model Core (Transgenic Core) as Managing Director.
The incoming Transgenic Core Managing Director will assume direction of a highly experienced team, which serves the needs of University of Michigan’s extensive research community. Having created thousands of mouse and rat models since its inception in 1989, the Transgenic Core is one of the oldest and most productive research cores at the University of Michigan and enjoys a long-standing international reputation of leadership and excellence. The incoming Managing Director, in partnership with the BRCF leadership team, will shape the future of the Core to ensure that it continues to produce transgenic animal models with cutting-edge technology for a diverse and growing group of research scientists and physicians.
For an overview of the Transgenic Core, please visit: https://brcf.medicine.umich.edu/cores/transgenic-animal-model/
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Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
- Excellent medical, dental and vision coverage effective on your very first day
- 2:1 Match on retirement savings
Science & Technology Expertise
Keeping up to date on the genome editing and transgenic technologies to identify methods that improve the range and efficiency of transgenic rodent models for the research community
Collaborating with scientific investigators to determine the best animal model for their research program
Advising Core users on how to design projects with genetically engineered mice and rats, and identifying the ideal technology for their application
Working with off-campus project collaborators in the design and validation of customized genome-editing reagents, transgenes, and gene-targeting vectors
Leading a hands-on training program in transgenic technology for Core users
Serving as a subject matter expert in transgenic rodent models and representing the Core as a scientific ambassador to the transgenic technology research community
Presenting the Core’s scientific achievements at local, national, and international meetings
Core Operations Management
Developing and implementing the Core’s strategic plan and vision
Directing and participating in the day-to-day operations of the Core
Optimizing workflows to ensure consistent, reliable, and timely production of genetically engineered rodent models
Initiating projects and managing expectations of Core users
Tracking project status and recording success rates
Supporting Core users with letters of support to granting agencies and preparations of progress reports and manuscripts
Developing and maintaining standard operating procedures
Keeping track of Core expenditures pertinent to supplies of animals, reagents, equipment, and repairs
Working with BRCF leadership and Core scientific advisory committee to enhance service offerings
Collaborating with other BRCF cores to further promote team science
Human Resource Management
Sourcing, interviewing, and selecting staff
Overseeing staff on-boarding and on-going staff training opportunities
Planning and directing Core staff schedules
Evaluating staff productivity and efficiency
Working with the BRCF administration office to identify and provide professional development opportunities for staff
Creating/sustaining a diverse and inclusive work environment that is effective for team building and morale
Managing expenses, and revenues through the use of institutional core management software, as well as preparation of an annual Core report and its presentation to the BRCF leadership team
Working with the BRCF administration office to set, monitor, and evaluate recharge rates for the Core and set annual budgets
Interfacing with billing and reporting software as well as University of Michigan IT to enhance usability, troubleshoot issues, and ensure timely & accurate billing
- A Ph.D. or equivalent doctoral degree in the biological sciences, preferably with a focus on genetics, molecular biology, or transgenic animal technology
- 3-5 years of postdoctoral or equivalent experience working in transgenic animal model generation with transgenic technology
- Demonstrated expertise in CRISPR technology and its applications in transgenesis
- Demonstrated expertise in designing gene targeting projects in mice, rats, and mammalian cells
- Demonstrated expertise in configuring and implementing genotyping assays
- Demonstrated effectiveness in managing highly experienced professional staff members and championing their efforts
- Demonstrated technical expertise in adapting advanced equipment in transgenesis procedures
- Excellent communication and organizational skills with the ability to work in a diverse, customer-based fee-for-service environment
- Significant experience in transgenic animal model generation with CRISPR technology
- 5-10 years of experience in embryonic stem cell technology, random DNA transgenesis, and genotyping assays
- Experience in designing and implementing genotyping assays for de novo genetically engineered mice and rats
- Experience with the generation of genetically engineered mice, rodent assisted reproductive technology services (ARTS)
- Demonstrated expertise in cryopreservation and assisted reproductive technology for rodents
- Rank of appointment, including at the faculty (research) level, based on qualifications and experience
The Michigan Medicine Biomedical Research Core Facilities are firmly committed to advancing Inclusion, Diversity, Equity, Accessibility, and Belonging which are core values at the Office of Research. Our community supports recruiting and cultivating a diverse workforce, as it is a reflection of our commitments to serve the diverse people of Michigan and the world. We strive to create a work culture where every team member feels respected, valued, and safe.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
How to Apply
A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
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The University of Michigan is an equal opportunity/affirmative action employer.
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