RESEARCH SCIENTIST 3

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Salary: Salary is commensurate with qualifications and experience.

Shift: First Shift

Notes: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.

The Freedman Lab in the Division of Nephrology, Department of Medicine, is seeking a Research Scientist 3 to lead projects using human pluripotent stem cells to develop new treatments for kidney disease, under the general guidance/supervision of Associate Professor Benjamin Freedman. The Research Scientist 3 will combine stem cell culture and differentiation with bioengineering, microfluidics, and pre-clinical animal models to build next-generation models of human kidney regeneration and disease. This position will be responsible for contributing to preparation of reports, papers, presentations and new proposals. The Research Scientist 3 will contribute to positive colleague and investigator relationships through interactions on current grants. The successful candidate will also assist Dr. Freedman with mentoring of trainees. Experience with animals is a plus.

This position will be located at South Lake Union campus of UW Medicine, a bastion of stem cell research in the innovative center of Seattle. The successful candidate will be detail-oriented, reliable, highly organized, possess a high degree of accountability for quality of work performed, can work independently and has excellent technical skills.

RESPONSIBILITIES

Experimental duties:
• Animal work - husbandry, injection, analysis and surgery relevant to kidneys
• Cell culture - daily differentiation and mainteinance of human pluripotent stem cells
• Microscopy - immunofluorescence, confocal, wide-field, live cell
• Microfluidics - bioengineering, device preparation, input/output bioanalysis
• Genome editing - guide RNA construction, transfection, screening
• Drug discovery - design and execution of high throughput screening assays
• Biochemistry and molecular biology - qPCR, electrophoresis, immunoblotting, cloning
• Computing and analysis - Illustrator, Powerpoint, Excel, Word, ImageJ, HTML
• Documentation - daily record of work performed in files and laboratory notebook

Scholarship:
• Contribute data and ideas for new projects
• Draft of new grants with minimal supervision
• Prepare primary research manuscripts with minimal supervision
• Write invited manuscripts
• Assist in seeking/acquiring additional funding
• Manage relationships with grants sponsors and progress reports

Animal care:
• Data collection/maintenance management for rodent colony
• Updating and ensuring compliance with animal welfare protocols
• Oversight of junior trainees working in the animal facility
• Demonstration and training of surgeries
• Developing new animal protocols

Lab duties:
• Mentor research trainees and undergraduates; contribute to improvements in efficiency
• Orient/train new staff
• Manage projects of moderate size and scope
• Assemble and organize research teams
• Lead projects or project tasks toward research objectives
• Inventory management for reagents/orders/cells; track expenses
• Ensure compliance with lab regulations and completion of corresponding paperwork

MINIMUM REQUIREMENTS
Bachelor's degree in biology, bioengineering, biophysics or related field and at least three years of experience or equivalent combination of education and experience.

Additional requirements:
Cell culture skills and experience; strong computer skills including Excel, statistical and/or graphical software (ex. Adobe Illustrator, ImageJ, PowerPoint); excellent organizational and communication skills; ability to manage diverse tasks; flexibility in work hours; a thirst for scientific knowledge and progress; comfort working with animal model; and a high degree of integrity.

Equivalent education and/or experience may substitute for minimum requirements.

DESIRED REQUIREMENTS
Experience with human pluripotent stem cells, high throughput screening, genome editing (CRISPR/Cas9), or rodent microsurgery.

CONDITIONS OF EMPLOYMENT
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.

Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law .

Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.

To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or dso@uw.edu .
COVID-19 VACCINATION REQUIREMENT
Governor Inslee's Proclamation 21-14.2 requires employees of higher education and healthcare institutions to be fully vaccinated against COVID-19 unless a medical or religious exemption is approved. Being fully vaccinated means that an individual is at least two weeks past their final dose of an authorized COVID-19 vaccine regimen. As a condition of employment, newly hired employees will be required to provide proof of their COVID-19 vaccination. View the Final candidate guide to COVID-19 vaccination requirement webpage for information about the medical or religious exemption process for final candidates.